Results 111 to 120 of about 980,527 (327)

Chronic alcohol consumption compromises gut barrier integrity and promotes endotoxemia: Implications for sepsis susceptibility in immunocompromised hosts

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Chronic alcohol exposure disrupts intestinal barrier integrity, resulting in a leaky gut and enhanced translocation of lipopolysaccharide (LPS) and microbial products into the systemic circulation. Alcohol‐induced endotoxemia drives exaggerated pro‐inflammatory responses, mitochondrial damage, and activation of the cGAS–STING pathway, particularly in ...
Thansita Bhunyakarnjanarat   +5 more
wiley   +1 more source

The role of abusive supervision on job tension and employees deviance of selected banks in Najafabad city, mediation by self-regulation role

open access: yesمشاوره شغلی و سازمانی, 2020
Aim: The purpose of this study was to investigate the effect of abusive supervision on job tension and deviance among employees of selected banks in Najaf Abad city with their self-regulatory mediator role.
محمد حکاک   +1 more
doaj  

Animal research in the UK: Regulation, implementation, welfare and development of new approach methodologies

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Scientific research with animals in the UK is regulated by the Animals (Scientific Procedures) Act 1986 with the National Centre for the Replacement, Refinement and Reduction of Animals in Research providing support for best practice and facilitating development of new approach methodologies.
Ewan St. John Smith   +6 more
wiley   +1 more source

Understanding the linkage between abusive supervision and counterproductive work behavior: the role played by resilience and psychological contract breach

open access: yesCogent Business & Management
A productive and positive workplace culture is essential to gaining positive organizational work outcomes. At the same time, counterproductive work behaviour in Punjab has been observed as a prevailing negative behaviour that hinders positive workplace ...
Muhammad Rizwan Sabir   +4 more
semanticscholar   +1 more source

Nanoclay‐Engineered Scaffolds for the Controlled Delivery of Biomolecules in Regenerative Medicine

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Regenerative medicine combines biomaterials, cells, scaffolds, and bioactive agents via modern technologies to aid in the reconstruction and repair of damaged tissues. Among these, nanoclay scaffolds have demonstrated unique advantages in facilitating the delivery of therapeutic agents.
Mehri Shadi   +2 more
wiley   +1 more source

Anatomists' experience and perspectives on the international transfer of human remains for the purpose of education

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Anecdotally, educational institutions without access to human remains may choose to import these from other countries; however, there is currently no published information illuminating the existence of this trade. This study therefore aimed to document the nature of international transfer of human remains for education, and explore anatomists'
Jackie Hazelhurst   +7 more
wiley   +1 more source

Understanding Predatory Lending: Moving Toward a Common Definition and Workable Solutions [PDF]

open access: yes, 1999
To date, various parties have used the term "predatory lending" to describe a wide range of abuses. Regulators, industry and advocates have not agreed on a single definition, but have used the term individually to refer to different practices and loan ...
Deborah Goldstein
core  

Effect of carbamazepine on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader, in healthy adults

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To evaluate the effects of carbamazepine, a strong cytochrome P450 (CYP)3A4 inducer, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera estrogen receptor degrader. Methods This was a phase 1, open‐label, fixed‐sequence, two‐period study in healthy adult participants.
Hechuan Wang   +7 more
wiley   +1 more source

Siege and Response: Families’ Everyday Lives and Experiences with Children’s Residential Mental Health Services (FULL REPORT) [PDF]

open access: yes, 2003
Purpose Our purpose in interviewing parents with a child placed in residential mental health treatment was threefold: (1) to understand the functioning of children requiring residential mental health treatment before, during, and after treatment; (2) to ...
Adams, Gerald R.   +3 more
core   +1 more source

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