Results 41 to 50 of about 9,130,475 (318)
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Makerspaces allow people to create and learn in a supportive environment and are growing in popularity. Hear how university libraries across the UK are creating different types of makerspace to support the hands-on learning of their wider academic communities.
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
DESIGN OF WEB BASED ACADEMIC INFORMATION SYSTEM IN MADRASAH IBTIDAIYAH NURUL FALAH DEPOK
The Covid-19 pandemic requires adaptation to the New Normal in its application. Madrasah Ibtidaiyah Nurul Falah Depok designed a web-based application to bridge this so that information about students reaches their parents without having to come to ...
Ibnu Rusdi, Bekti Kurniasih
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Typical Academic Electronic Library Creation.
In article results of G.I.Denisenko NTUU “KPI” NTL information funds structure analysis were presented in the context of topical collection of documents, readership category, documents types.
A. Savitsky +5 more
doaj
The Impact of a Camp Orientation Program on First-Year Academic Engagement and Persistence
More and more, institutions of higher education are being held accountable for student success measures such as persistence and completion rates. If research indicates that higher levels of student engagement lead to better academic outcomes, it is then ...
Michael R. Haynes, T. Wayne Atchley
doaj +1 more source

