Results 41 to 50 of about 9,130,475 (318)

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Academic Makerspaces [PDF]

open access: yes, 2017
Makerspaces allow people to create and learn in a supportive environment and are growing in popularity. Hear how university libraries across the UK are creating different types of makerspace to support the hands-on learning of their wider academic communities.
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

DESIGN OF WEB BASED ACADEMIC INFORMATION SYSTEM IN MADRASAH IBTIDAIYAH NURUL FALAH DEPOK

open access: yesJurnal Riset Informatika, 2020
The Covid-19 pandemic requires adaptation to the New Normal in its application. Madrasah Ibtidaiyah Nurul Falah Depok designed a web-based application to bridge this so that information about students reaches their parents without having to come to ...
Ibnu Rusdi, Bekti Kurniasih
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Typical Academic Electronic Library Creation.

open access: yesÌнформаційні технології в освіті, 2009
In article results of G.I.Denisenko NTUU “KPI” NTL information funds structure analysis were presented in the context of topical collection of documents, readership category, documents types.
A. Savitsky   +5 more
doaj  

The Impact of a Camp Orientation Program on First-Year Academic Engagement and Persistence

open access: yesJournal of College Orientation, Transition, and Retention, 2013
More and more, institutions of higher education are being held accountable for student success measures such as persistence and completion rates. If research indicates that higher levels of student engagement lead to better academic outcomes, it is then ...
Michael R. Haynes, T. Wayne Atchley
doaj   +1 more source

Academic Ideals [PDF]

open access: yesScience, 1905
Mode of access: Internet.
openaire   +2 more sources

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