Results 61 to 70 of about 3,824,185 (409)

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Mobile Phone Addiction and Academic Procrastination Negatively Impact Academic Achievement Among Chinese Medical Students

Frontiers in Psychology, 2021
The problem of mobile phone addiction and academic procrastination among medical students has been widely acknowledged. This study aimed to explore the influence of demographic factors on mobile phone addiction, academic procrastination, and academic ...
Jing Tian, Ji-yang Zhao, Jia-ming Xu, Qing-lin Li, Tao Sun, Chen-xi Zhao, Rui Gao, Li-yan Zhu, Hai-chen Guo, Li-bin Yang, De-pin Cao, Shu-e Zhang   +11 more
doaj   +1 more source

Ellie Karle Won First Prize in Poster Competition [PDF]

, 2016
Much research has focused on the variables associated with student academic outcomes indicated by class grades. This study explored the influence of student goal orientation on academic achievement based on a trichotomous model: mastery goals (motivated ...

core   +1 more source

The Importance of Students’ Motivation for Their Academic Achievement – Replicating and Extending Previous Findings

Frontiers in Psychology, 2019
Achievement motivation is not a single construct but rather subsumes a variety of different constructs like ability self-concepts, task values, goals, and achievement motives.
R. Steinmayr, Anne F. Weidinger, Malte Schwinger, Birgit Spinath   +3 more
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Prediction of academic achievement based on emotional intelligence and achievement motivation among students of Islamic Azad University of Roudehen branch in 2013

پژوهان, 2015
Introduction: Study of effective factors on development or academic performance is rather complex because this concept has extensive dimensions which both environmental and individual factors affect it.
Ali Asghar Hossein Mardi, Zahra Hossein Mardi   +1 more
doaj  

THE INFLUENCE OF LEARNING OUTCOMES PRODUCTIVE SUBJECTS AND SELF-RELIANCE LEARNING WITH ACHIEVEMENT INDUSTRIAL WORK PRACTICES STUDENTS OF GRADE XII ELECTRONICS ENGINEERING SKILLS PROGRAM AT SMKN 3 YOGYAKARTA ACADEMIC YEAR 2012/2013 [PDF]

, 2013
This study aimed to determine: (1) the influence of Learning Outcomes Productive Subjects with Achievement Industrial Work Practices students of grade XII Electronics Engineering Skills Program at SMKN 3 Yogyakarta Academic Year 2012/2013.
Afni Nur, Anita
core  

Stress, coping strategies and academic achievement in teacher education students

European Journal of Teaching and Education, 2019
University students experience stress, and how they cope with this stress affects their academic achievement. This study examined stress in teacher education students and had three objectives: to describe different degrees of stress and coping styles; to
Josep Gustems-Carnicer, C. Calderón, Diego Calderón-Garrido   +2 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

BENARKAH SELF ESTEEM MEMPENGARUHI PRESTASI AKADEMIK?

Humanitas: Indonesian Psychological Journal, 2016
Self-esteem determines a person’s overall mental development, it can even affect human behavior. The debate arose when researchers try to explain, whether student achievement is influenced by self-esteem?
Satrio Budi Wibowo
doaj   +1 more source