Results 51 to 60 of about 7,314,511 (242)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Forced to Conform? Using Common Processes and Standards to Create Effective eLearning
Journal of Interactive Media in Education, 2004 : Working on multiple large-scale eLearning projects forces teams to try and standardise processes and procedures. Tools such as XML allow us to manipulate and exploit content in ways previously impossible.
Marion Manton +3 more
doaj +1 more source
Handbook of Indicators of Institutionalization of Academic Disciplines in SSH
Serendipities, 2020 This is the handbook of indicators with which the comparative research on the insitutionalization of several academic disciplines in the social sciences and humanities has been organised within the EU-funded project INTERCO-SSH.
Fleck Christian, Karády Victor
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Journal of Interactive Media in Education, 2004 : Archaeology has always been a multimedia discipline in terms of teaching and publication. From the earliest days of archaeology as an academic subject, archaeologists have used museum collections, slides, and actual site visits as well as 'chalk and ...
Lucia Nixon, Simon Price
doaj +1 more source
Фармацевтичний журнал, 2020 Based on the results of the Licensed Integrated Exam (LIЕ), the level of knowledge of students and interns of higher educational institutions of medical direction is determined, a decision is made on the possibility of their further study and work, and a
Ya. O. Hrynkiv +3 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Mind Presentation in Graphic Narrative: A Re-contextualization of Narrative Theory in Marjane Satrapi’s Persepolis [PDF]
Maǧallaẗ Buḥūṯ Al-Šarq Al-Awsaṭسبر أغوار العقل في السرد الرسومي: إعادة صياغة السرد في رواية "برسيبوليس" لمارجين ساترابييعكس التشكيل الأكاديمي الناشئ لفن القصص المصورة تأثير التحالفات مع تخصصات أخرى مثل دراسات النوع الاجتماعي، وما بعد الاستعمار، والماركسية، والسير الذاتية، مما يؤكد على
داليا سعد محمد منصور منصور
doaj +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source