Results 61 to 70 of about 923,068 (299)

Styl czy dyskurs naukowy? Perspektywa historyczna

open access: yesForum Lingwistyczne, 2018
Academic Style or Discourse? A Historical Perspective The work concerns the usefulness of terms “style” and “discourse” in research of academic Polish evolution.
Artur Rejter
doaj  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Discourse functions of formulaic sequences in academic speech across two disciplines [PDF]

open access: yes, 2014
Formulaic sequences play a crucial role in building academic discourse. From among the variety of formulaic expressions, lexical bundles have been shown to serve particular facilitative functions in academic discourse.
Chan, Swee Heng, Hadi Kashiha,
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Text disintegration within the academic discourse

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2018
In line with the ideas of communicative linguistics, the text is considered as a product of discursive activity, as a means of realizing addressant’s intentions.
D.A. Cheremokhina, K.K. Stebunova
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Evidential adjectives in Lithuanian academic discourse

open access: yesKalbotyra, 2012
The present study explores the functional distribution of the neuter adjectives akivaizdu ‘evident, obvious’, aišku ‘clear’, natūralu ‘natural’ and panašu ‘likely’ in Lithuanian written academic discourse.
Anna Ruskan
doaj   +1 more source

Student identity: transitions through project work [PDF]

open access: yes, 2016
Students entering higher education in the UK must be able to learn independently and understand how knowledge is constructed in their future academic community.
Elmslie, Rachel, Lewis, Siriol
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Home - About - Disclaimer - Privacy