Results 61 to 70 of about 44,975 (256)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

FOSTERING ACADEMIC LITERACY AND ACADEMIC WRITING IN UNIVERSITY: FROM THEORY TO PRACTICE

Высшее образование в России, 2016
The paper addresses the theoretical and practical aspects of developing academic literacy of students. It overviews the nature and the structure of academic literacy and claims that academic literacy should be developed on the basis of academic discourse.
Natalia V. Smirnova
doaj  

Literature citation and writer identity construction in linguistic academic discourse. [PDF]

Heliyon, 2023
Liu W, Zhang Y.
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Dynamics and landscape of academic discourse on environmental attitudes and behaviors since the 1970s. [PDF]

Front Sociol, 2023
Telesiene A, Hadler M.
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Academic discourse on education during the early part of the pandemic. [PDF]

Heliyon, 2022
Meulenbroeks R, Reijerkerk M, Angerer E, Pieters T, Bakker A.   +4 more
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

AI-Mediated Academic Discourse and Language Identity: A Critical Discourse Analysis of Meaning-Making in Higher Education

Studies in Linguistics and Language Education
This study examines AI-mediated academic discourse as a site of meaning-making and language identity construction in higher education through Critical Discourse Analysis (CDA).
Prisca Boniphace Makulilo, Emmanuel Selemani Shindika, Bertha Anthony Maturo   +2 more
doaj