Results 121 to 130 of about 12,486,217 (204)

An Engineered HR1‐Stem Helix‐HR2 Trimeric Platform for Developing Broad‐Spectrum Coronavirus Vaccines

Advanced Science, EarlyView.
Sun et al. report a self‐assembling trimeric subunit vaccine platform termed RHS, which integrates the JN.1 receptor‐binding domain (RBD) with the heptad repeat 1 (HR1), stem helix (SH), and heptad repeat 2 (HR2) regions. The SARS‐CoV‐2 RHS vaccine elicits variant‐reactive RBD‐specific antibodies and cross‐reactive SH‐specific antibodies against ...
Xikui Sun, Junhao Fan, Xiaolu Xie, Yuting Shi, Xiaoqing Liu, Tiefeng Xu, Sidi Yang, Keda Shi, Chengshu Xie, Shixiong Li, Siwen Chen, Ruoxi Cai, Ping He, Yuzhen Ye, Tao Chen, Xiancai Ma, Chunmei Li, Jingyou Yu, Deyin Guo   +18 more
wiley   +1 more source

Academic Self-Efficacy and Future Time Perspective Predict Academic Procrastination: The Mediating Function of Academic Self-Control

International Journal of Body, Mind and Culture
Background: Background: Academic procrastination is increasingly recognized as a detrimental factor that negatively affects student success, achievement, and mental health.
Riza Noviana Khoirunnisa, Budi Eko Soetjipto, Tutut Chusniyah, Hetti Rahmawati , Chinun Boonroungrut   +4 more
doaj   +1 more source

Native American Studies Program APR Self Study

, 2014
Native American Studies Program Academic Program Review Self Study ReportNative American Studies Program Academic Program Review Self Study ReportNative American Studies ...
Native American Studies Program Academic Program Review Self Study Report, APR Self Study Report
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Parenting Styles and Self-Efficacy of Adolescents: Malaysian Scenario [PDF]

, 2013
Parenting styles and its impact on adolescents psychosocial development has been an area of interest in the field of psychology Previous studies have revealed that parenting styles are correlated with adolescents self-esteem drug and alcohol use
Amudha Kadirvelu, Dr. Cai-Lian Tam, Amanda Chong   +2 more
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A Huaxian Formula Nanoformulation Confers Protection Against Acute Radiation‐Induced Lung Injury by Targeting Ferroptosis

Advanced Science, EarlyView.
An inhalable, nanoengineered herbal therapy achieves protection against acute radiation‐induced lung injury via self‐assembled nanomicelle‐mediated pulmonary targeting and a previously unrecognized dual mechanism that attenuates oxidative stress while inhibiting ferroptosis in alveolar epithelial cells.
Li Quan, Junyang Chen, Xingmin Chen, Zengyi Fang, Yuanzhen Mi, Pingjin Zou, Shunlian Fu, Huakang Li, Ke Xu, Bing Lin, Jinyi Lang, Meihua Chen   +11 more
wiley   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

Advanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen, Ming Li, Xuesheng Wang, Jiajia Sun, Ziyuan Zhang, Yongfeng Gong, Benkang Shi, Nengwang Yu, Yunuo Mao, Shengtian Zhao, Xiulin Zhang, Liqiang Guo   +11 more
wiley   +1 more source

How depression affects academic self-efficacy among college students: the mediating effect of professional identity and the moderating effect of belief in a just world

BMC Public Health
Background Academic self-efficacy has a significant impact on college students' academic performance and growth and success. Purpose To explore the effects of depression on academic self-efficacy and the mediating role of professional identity and the ...
Chunmei Chen, Yujie Zhu, Yitong Hong, Fanghao Xiao, Li Li   +4 more
doaj   +1 more source

Discovery and Optimization of AMT‐676, a CDH17‐Targeting ADC for the Treatment of Advanced Gastrointestinal Cancers

Advanced Science, EarlyView.
AMT‐676 is a novel antibody‐drug conjugate targeting CDH17, an adhesion molecule uniquely exposed on gastrointestinal tumor surfaces. Engineered with an optimized exatecan payload, it demonstrates profound tumor regression and a robust bystander effect across diverse preclinical models.
Ying‐nan Wang, Dan‐yun Ruan, Jing Shi, Yue Huang, Hui Sheng, Ya‐ling Huang, Linjie Ma, Lijun Wang, Caiwei Chen, Yixuan Wang, Yue Zhang, Yi Shen, Qing Zhang, Jianjian Zhang, Yanfang Tang, Jin‐ling Zhang, Jia‐jia Hu, Chen‐yi Wu, Jia‐ying Chen, Xun Meng, Shu‐Hui Liu, Feng Wang   +21 more
wiley   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

Motivational Belief And Self-Regulated Learning A Study On Malaysian Students. [PDF]

, 2006
This study explored the relationships between self-regulated learning and selected motivational beliefs, namely self-efficacy, control beliefs, and anxiety of Malaysian ...
Abu Bakar, Kamariah, Melissa Ng, Lee Yen Abdullah   +1 more
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