Results 51 to 60 of about 55,832 (307)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Campus & alumni news [PDF]

open access: yes, 2004
Boston University Medicine was published by the Boston University Medical Campus, and presented stories on events and topics of interest to members of the BU Medical Campus community.

core  

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

CONSIDERATIONS REGARDIND THE SCIENTIFIC GROUNDS FOR SETTING UP SECURITY STRATEGIES [PDF]

open access: yesAnnals: Series on Military Sciences, 2016
The main objective of the paper is to present a point of view on scientific approaches towards the security strategy so as to create opportunities to intensify the exchange of scientific ideas between scientists.
Mihai ILIESCU, Eugen SITEANU
doaj  

Scaling Up: Reform Lessons for Urban Comprehensive High Schools [PDF]

open access: yes, 2005
Policy interest in the challenge of improving urban high schools has grown recently, as high-profile business leaders and politicians have called the preparedness of graduates for college work into question.

core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Audiovisual research collections and their preservation [PDF]

open access: yes, 2008
The basic problem of primary audio and video research materials is clearly shown by the survey: A great and important part of the entire heritage is still outside archival custody in the narrower sense, scattered over many institutions in fairy small ...
Schüller, Dietrich
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Real-Time Systems: Reflections on higher education in the Czech Republic, Hungary, Poland and Slovenia [PDF]

open access: yes, 2003
Real-time systems (An ICT definition)\ud In real-time multiprocessing there is the extra requirement that the system complete its response to any input within a certain critical time.
File, Jon, Goedegebuure, Leo
core   +1 more source

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