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Acanthamoeba is free-living protist pathogen capable of causing a blinding keratitis and granulomatous encephalitis. However, the mechanisms of Acanthamoeba pathogenesis are still not clear.
Jian-Ming Huang+6 more
doaj +1 more source
Contact Lens-Associated Acanthamoeba Keratitis in Iran [PDF]
Acanthamoeba keratitis is a vision-threatening infection caused by pathogenic species of the genus Acanthamoeba. In this study, 13 Acanthamoeba keratitis cases were diagnosed among 52 keratitis patients.
AH Maghsood+4 more
doaj +1 more source
Assessing Acanthamoeba cytotoxicity: comparison of common cell viability assays
BackgroundIn vitro models for studying interactions between Acanthamoeba and host cells are crucial for understanding the pathomechanism of Acanthamoeba and assessing differences between strains and cell types.
Alvie Loufouma Mbouaka+5 more
doaj +1 more source
Acanthamoeba encephalitis in immunocompetent hosts: A report of two cases
Acanthamoeba are ubiquitous free-living amoeba. Acanthamoeba infections cause necrotizing vasculitis, resulting in vessel thrombosis and cerebral infarction. Acanthamoeba CNS infections, though uncommon, are associated with high mortality.
Sohini Das+6 more
doaj +1 more source
An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment
Free-living amoebae of the genus Acanthamoeba are causal agents of a severe sight-threatening infection of the cornea known as Acanthamoeba keratitis. Moreover, the number of reported cases worldwide is increasing year after year, mostly in contact lens ...
J. Lorenzo-Morales+2 more
semanticscholar +1 more source
Validation of reference genes for the normalization of RT-qPCR gene expression in Acanthamoeba spp.
Acanthamoebae are potentially pathogenic organisms, with a highly unique, yet still insufficiently investigated metabolism. Many open questions can be addressed by gene expression studies, however, for Acanthamoeba reliable standards have not yet been ...
M. Köhsler+3 more
semanticscholar +1 more source
Acanthamoeba protease activity promotes allergic airway inflammation via protease-activated receptor 2. [PDF]
Acanthamoeba is a free-living amoeba commonly present in the environment and often found in human airway cavities. Acanthamoeba possesses strong proteases that can elicit allergic airway inflammation.
Mi Kyung Park+5 more
doaj +1 more source
Purpose To evaluate the incidence of Acanthamoeba keratitis in the Netherlands between 2009 and 2015 and to analyse predicting factors for treatment outcome.
Anna C Randag+9 more
semanticscholar +1 more source
Acanthamoeba spp. are the causative agent of Acanthamoeba keratitis and granulomatous amoebic encephalitis (GAE). The current options to treat Acanthamoeba infections have limited success.
Areeba Anwar+7 more
semanticscholar +1 more source
Species, Sequence Types and Alleles: Dissecting Genetic Variation in Acanthamoeba
Species designations within Acanthamoeba are problematic because of pleomorphic morphology. Molecular approaches, including DNA sequencing, hinted at a resolution that has yet to be fully achieved. Alternative approaches were required. In 1996, the Byers/
P. Fuerst, G. Booton
semanticscholar +1 more source