Acanthamoeba castellanii–Mediated Reduction of Interleukin-1β Secretion and Its Association With Macrophage Autophagy [PDF]
ScientificaNoncanonical autophagy including unconventional protein secretion has been extensively studied. Our work focused on a leaderless IL-1β protein secretion from human macrophage in response to Acanthamoeba castellanii components, Acanthamoeba culture ...
Rachasak Boonhok +11 more
doaj +3 more sources
Recombinant protein expression in Acanthamoeba castellanii [PDF]
Frontiers in Bioengineering and BiotechnologyThe ongoing quest to improve protein production efficiency, quality, and versatility fuels the exploration of novel expression systems. In this research, we explored the potential of the axenically culturable Acanthamoeba as an alternative for producing ...
Pooja Salunke +4 more
doaj +4 more sources
The Activity of Polyhomoarginine against Acanthamoeba castellanii [PDF]
Biology, 2022 Arginine-rich peptides can have broad-spectrum anti-bacterial and anti-fungal activities. Polyhomoarginine consists of highly cationic residues which can act on the negatively charged microbial cell membranes.
Hari Kumar Peguda +4 more
doaj +5 more sources
Nitroxoline evidence amoebicidal activity against Acanthamoeba castellanii through DNA damage and the stress response pathways [PDF]
International Journal for Parasitology: Drugs and Drug ResistanceAcanthamoeba castellanii is a widespread unicellular eukaryote found in diverse environments, including tap water, soil, and swimming pools. It is responsible for severe infections, such as Acanthamoeba keratitis and granulomatous amebic encephalitis ...
Lijun Chen +5 more
doaj +3 more sources
Survival of Bordetella bronchiseptica in Acanthamoeba castellanii. [PDF]
Microbiol Spectr, 2023 The pathogenic bacterium Bordetella bronchiseptica , which causes respiratory diseases in various mammals, exhibits distinct Bvg + and Bvg − phenotypes. The former represents the virulent phase, in which the bacteria express a set of virulence factors, while the role ...
Nugraha DK +5 more
europepmc +4 more sources
Encystment and Excystment Processes in Acanthamoeba castellanii: An Emphasis on Cellulose Involvement [PDF]
PathogensThe free-living amoeba Acanthamoeba castellanii is a unicellular eukaryote distributed in a wide range of soil or aquatic environments, either natural or human-made, such as rivers, lakes, drinking water, or swimming pools.
Mathew Choaji +4 more
doaj +4 more sources
Metronidazole conjugated magnetic nanoparticles loaded with amphotericin B exhibited potent effects against pathogenic Acanthamoeba castellanii belonging to the T4 genotype [PDF]
AMB Express, 2020 Acanthamoeba castellanii can cause granulomatous amoebic encephalitis and Acanthamoeba keratitis. Currently, no single drug has been developed to effectively treat infections caused by Acanthamoeba.
Sumayah Abdelnasir +6 more
doaj +2 more sources
Ribosomal Phosphoproteins in Acanthamoeba castellanii [PDF]
European Journal of Biochemistry, 1981 Ribosomes and subunits from Acanthamoeba castellanii were purified. The pattern of ribosomal proteins was analysed by two‐dimensional get electrophoresis. The small subunit of cytoplasmic ribosomes contains 25 and the large 40 proteins. After incubation of exponentially growing cells with ortho[33P]phosphate for 1 j, one basic protein of the small ...
Helga Jantzen
openalex +3 more sources
Inhibitory Effect of a Novel Ophthalmic Solution on Acanthamoeba castellanii Adhesion and Biofilm Formation on Human Corneal Epithelium [PDF]
LifeBackground/Objectives: Acanthamoeba keratitis (AK) is a rare but sight-threatening corneal infection, often associated with contact lens wear and resistant to conventional therapies.
Francesco D’Oria +8 more
doaj +2 more sources
Unveiling the molecular architecture of the mitochondrial respiratory chain of Acanthamoeba castellanii [PDF]
Microbial CellAcanthamoeba castellanii is a ubiquitous free-living amoeba that can cause severe infections in humans. Unlike most other organisms, A. castellanii possesses a “complete” mitochondrial respiratory chain, meaning it contains several additional enzymes ...
Christian Q. Scheckhuber +2 more
doaj +2 more sources