Results 31 to 40 of about 40,069 (236)

Homology Modeling, Molecular Docking, Molecular Dynamic Simulation, and Drug-Likeness of the Modified Alpha-Mangostin against the β-Tubulin Protein of Acanthamoeba Keratitis

Molecules, 2022
Acanthamoeba species are capable of causing amoebic keratitis (AK). As a monotherapy, alpha-mangostin is effective for the treatment of AK; however, its bioavailability is quite poor.
Tassanee Ongtanasup, A. Mazumder, A. Dwivedi, Komgrit Eawsakul   +3 more
semanticscholar   +1 more source

Challenges in Acanthamoeba Keratitis: A Review

Journal of Clinical Medicine, 2021
To review challenges in the diagnosis and management of Acanthamoeba keratitis (AK), along with prognostic factors, in order to help ophthalmologists avoid misdiagnosis, protracted treatment periods, and long-term negative sequelae, with an overarching ...
Giuseppe Varacalli, A. Di Zazzo, Tommaso Mori, Thomas H. Dohlman, Sara Spelta, M. Coassin, S. Bonini   +6 more
semanticscholar   +1 more source

Contact lenses contamination by Acanthamoeba spp. in Upper Egypt

PLoS ONE, 2021
Background Acanthamoeba spp. are one of the free-living amoeba that spread worldwide causing keratitis. Owing to the increase in the use of lenses, whether for medical or cosmetic purposes, the incidence of disease increases every year.
Faten A. M. Hassan, M. E. M. Tolba, Gamal H. Abed, H. M. Omar, Sara S. Abdel-Hakeem   +4 more
doaj   +2 more sources

Acanthamoeba Keratitis: an update on amebicidal and cysticidal drug screening methodologies and potential treatment with azole drugs

Expert Review of Anti-Infective Therapy, 2021
Introduction: Acanthamoeba encompasses several species of free-living ameba encountered commonly throughout the environment. Unfortunately, these species of ameba can cause opportunistic infections that result in Acanthamoeba keratitis, granulomatous ...
B. Shing, Mina Balen, J. McKerrow, Anjan Debnath   +3 more
semanticscholar   +1 more source

Dendrite-like anterior stromal keratitis coinfected with Acanthamoeba and Pseudomonas in an orthokeratology contact lens wearer

Taiwan Journal of Ophthalmology, 2019
Acanthamoeba species can cause a keratitis misdiagnosed as herpes keratitis or fungal keratitis. We report an unusual dendrite-like anterior stromal keratitis coinfected with Acanthamoeba and Pseudomonas aeruginosa in an orthokeratology contact lens ...
Chih-Chien Hsu
doaj   +1 more source

Treatment of recalcitrant Acanthamoeba Keratitis with Photoactivated Chromophore for Infectious Keratitis Corneal Collagen Cross-Linking (PACK-CXL)

American Journal of Ophthalmology Case Reports, 2022
Purpose: To describe a case of recalcitrant Acanthamoeba Keratitis (AK) complicated by medical non-compliance and medication intolerance that was successfully treated with photoactivated chromophore for infectious keratitis corneal collagen cross-linking
Shelly H. Watson, Nakul S. Shekhawat, Yassine J. Daoud   +2 more
doaj   +1 more source

Contact Lens-Associated Acanthamoeba Keratitis in Iran [PDF]

Iranian Journal of Public Health, 2005
Acanthamoeba keratitis is a vision-threatening infection caused by pathogenic species of the genus Acanthamoeba. In this study, 13 Acanthamoeba keratitis cases were diagnosed among 52 keratitis patients.
AH Maghsood, M Rezaian, F Rahimi, SA Ghiasian, Sh Farnia   +4 more
doaj   +1 more source

Evaluation of Acanthamoeba keratitis cases in a tertiary medical care centre over 21 years

Scientific Reports, 2021
To report on Acanthamoeba keratitis cases in a tertiary university eye-hospital in Graz, Austria, over a 21-year period. Retrospective study. Parameters included demographics, diagnostics, clinical courses, medical therapies, surgical interventions ...
Wolfgang List, Wilfried Glatz, R. Riedl, Georg Mossboeck, G. Steinwender, A. Wedrich   +5 more
semanticscholar   +1 more source

Silver Nanoparticles Conjugated with Contact Lens Solutions May Reduce the Risk of Acanthamoeba Keratitis

Pathogens, 2021
Acanthamoeba keratitis (AK), a severe sight-threatening corneal infection, has become a significant medical problem, especially among contact lens wearers.
E. Hendiger, Marcin Padzik, I. Sifaoui, M. Reyes-Batlle, Atteneri López-Arencibia, Diana Zyskowska, M. Grodzik, Anna Pietruczuk-Padzik, J. Hendiger, G. Olędzka, L. Chomicz, J. Piñero, J. Lorenzo-Morales   +12 more
semanticscholar   +1 more source

Oral miltefosine for refractory Acanthamoeba keratitis

American Journal of Ophthalmology Case Reports, 2019
Purpose: To report the first case of Acanthamoeba keratitis treated with oral miltefosine in the United States. Observations: A 17-year-old female with a history of orthokeratology contact lens wear presented after five months of left eye pain, redness ...
Kristin E. Hirabayashi, Charles C. Lin, Christopher N. Ta   +2 more
doaj   +1 more source