The Characterisation of an Adrenergic Signalling System Involved in the Encystment of the Ocular Pathogen Acanthamoeba spp. [PDF]
, 2016 The aim of this study was to identify and characterise the receptor system involved in controlling encystment in Acanthamoeba using specific agonists and antagonists and to examine whether endogenous stores of catecholamines are produced by the organism.
Abel +39 more
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In Vivo Confocal Microscopy Cellular Features of Host and Organism in Bacterial, Fungal, and Acanthamoeba Keratitis. [PDF]
, 2018 PURPOSE: To determine cellular features of fungal (FK), Acanthamoeba (AK), and bacterial keratitis (BK) using HRT3 in vivo confocal microscopy (IVCM). DESIGN: Prospective observational cross-sectional study.
Burton, Matthew J +8 more
core +1 more source
Automated Acanthamoeba polyphaga detection and computation of Salmonella typhimurium concentration in spatio-temporal images [PDF]
Micron (2011), 42, 911-920, 2010 Interactions between bacteria and protozoa is an increasing area of interest, however there are a few systems that allow extensive observation of the interactions. We examined a surface system consisting of non nutrient agar with a uniform bacterial lawn that extended over the agar surface, and a spatially localised central population of amoebae.
arxiv +1 more source
Ceratite por Acanthamoeba [PDF]
, 2000 Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Hospital São PauloUniversidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Departamento de OftalmologiaUNIFESP, EPM, Hospital São PauloUNIFESP, EPM ...
Alvarenga, Lênio Souza +2 more
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Silver Nanoparticles as a Novel Potential Preventive Agent against Acanthamoeba Keratitis
Pathogens, 2020 Free living, cosmopolitan amoebae from Acanthamoeba genus present a serious risk to human health. As facultative human parasites, these amoebae may cause Acanthamoeba keratitis (AK).
E. Hendiger +16 more
semanticscholar +1 more source
Prospective Study of the Diagnostic Accuracy of the In Vivo Laser Scanning Confocal Microscope for Severe Microbial Keratitis. [PDF]
, 2016 To determine the diagnostic accuracy of in vivo confocal microscopy (IVCM) for moderate to severe microbial keratitis (MK). Double-masked prospective cohort study.
Burton, MJ +12 more
core +1 more source
An update on Acanthamoeba keratitis: diagnosis, pathogenesis and treatment
Parasite, 2015 Free-living amoebae of the genus Acanthamoeba are causal agents of a severe sight-threatening infection of the cornea known as Acanthamoeba keratitis. Moreover, the number of reported cases worldwide is increasing year after year, mostly in contact lens ...
J. Lorenzo-Morales +2 more
semanticscholar +1 more source
PLoS ONE, 2020 Purpose To determine whether Acanthamoeba keratitis (AK) patients have higher rates of Acanthamoeba and free-living amoeba (FLA) colonising domestic sinks than control contact lens (CL) wearers, and whether these isolates are genetically similar to the ...
Nicole A. Carnt +3 more
semanticscholar +1 more source
Using phase II data for the analysis of phase III studies: an application in rare diseases [PDF]
Clinical Trials, 14(3):277-285, 2017, 2016 Clinical research and drug development in orphan diseases is challenging, since large-scale randomized studies are difficult to conduct. Formally synthesizing the evidence is therefore of great value, yet this is rarely done in the drug approval process.
arxiv +1 more source
The pathogenesis of Acanthamoeba infections: current status and future implications [PDF]
, 2004 Acanthamoeba are opportunistic protozoan parasites that can cause painful, visionthreatening keratitis. However the pathogenesis and pathophysiology of Acanthamoeba keratitis remain incompletely understood. Most cases of Acanthamoeba keratitis develop
Khan, Naveed Ahmed
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