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Are Acantholysis and Transglutaminase Inhibition Related Phenomena?
Dermatology, 2009Background: The loss of intercellular cohesion among keratinocytes (acantholysis) may be considered the histologic marker of pemphigus. Many drugs, especially thiol drugs, proved to be able to provoke in vitro acantholysis by biochemical mechanisms interfering with the disulfide and thiol group balance.
ESPOSITO C +5 more
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Ultrastructure of epidermocytes in true pemphigus acantholysis
Arkhiv patologii, 2019To investigate the ultrastructure of epidermocytes in skin biopsy specimens, by taking into account an update on the pathomorphogenesis of true pemphigus acantholysis.Affected skin biopsy specimens from 4 patients with Pemphigus vulgaris (a mixed mucosal-epidermal variant) and from 1 patient with P.
S G, Lykova +5 more
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Cantharidin-Induced Acantholysis
Archives of Dermatology, 1966Several known respiratory inhibitors were found to prevent cantharidin-induced acantholysis and also to block respiration in specimens of whole skin from the hairless mouse. The length of incubation required for the appearance of acantholysis was directly related to the rate of respiration, and inhibitors which produced only partial inhibition of ...
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Cantharidin-induced acantholysis.
The American Journal of dermatopathology, 1989Cantharidin has been used to induce acantholysis in vivo. Intraepidermal clefting starts at the junction between the basal and epidermal layers, and later involves all of the levels of the stratum spinosum. As a response to early acantholysis, an increased number of epibasal cells synthesize DNA. This is not related to an increased binding of epidermal
C, Piérard-Franchimont, G E, Piérard
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Archiv f�r Dermatologische Forschung, 1973
1. “Foreign cell acantholysis” is defined as a special type of microacantholysis that occurs in the epidermis in the course of exocytosis. Characteristic is the loss of single desmosomes or the loss of desmosomal contacts in limited areas of the surface of individual keratinocytes, and the concomitant rearrangement of the tonofilament system.
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1. “Foreign cell acantholysis” is defined as a special type of microacantholysis that occurs in the epidermis in the course of exocytosis. Characteristic is the loss of single desmosomes or the loss of desmosomal contacts in limited areas of the surface of individual keratinocytes, and the concomitant rearrangement of the tonofilament system.
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ACANTHOLYSIS: A FEATURE OF ACRODERMATITIS ENTEROPATHICA
Archives of Dermatology, 1971To the Editor.— Acrodermatitis enteropathica is an uncommon disorder characterized by diarrhea, alopecia, and a distinguishing skin eruption. The skin involvement is mainly that of crops of bullae and pustules appearing around the body orifices and over the extremities.1Paronychia, verrucose lesions, and candidiasis may be encountered.2It is sometimes
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Unilateral nipple erosion with acantholysis
International Journal of Dermatology, 2018Garima Dabas +3 more
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