Results 41 to 50 of about 2,893 (176)

Potential Pitfalls of IgG4 Immunohistochemical Staining on Lesional Tissue in Cutaneous Acantholytic Disorders

open access: yesDermatopathology
The diagnostic utility of immunohistochemistry on paraffin-embedded sections in bullous disorders is useful when frozen tissue is not available. In pemphigus vulgaris and pemphigus foliaceus, an intercellular lace-like staining pattern of IgG4 on ...
Carla Stephan, Linglei Ma
doaj   +1 more source

Epidermolysis Bullosa Classification and Current Approach to Diagnosis

open access: yesPediatric Dermatology, Volume 43, Issue S2, Page 5-15, August 2026.
ABSTRACT Epidermolysis bullosa (EB) is a heterogeneous group of rare genodermatoses marked by skin fragility and bullae formation induced by minor trauma. Pathologic variants in at least 21 genes are associated with EB, grouped into four major subtypes based predominantly on the plane of cleavage within the skin.
Hannah E. Mumber, Marissa J. Perman
wiley   +1 more source

Phosphorylated p38 mitogen-activated kinase in patients with pemphigus vulgaris: a case–controlled study

open access: yesJournal of the Egyptian Women’s Dermatologic Society, 2020
Background Although the exact pathogenic mechanisms leading to blister formation in pemphigus vulgaris (PV) have not been fully elucidated, intracellular signaling following antibody binding has been found to be necessary for inducing cell-cell ...
Shereen A Sobeih   +4 more
doaj   +1 more source

Drug-related pityriasis rubra pilaris with acantholysis [PDF]

open access: yesVojnosanitetski Pregled, 2013
Introduction. Acantholysis is rarely reported histological feature of Pityriasis rubra pilaris (PRP), recently recognized as having diagnostic specificity for differentiating PRP from psoriasis. Case report.
Gajinov Zorica T.   +5 more
doaj   +1 more source

Scanning electron microscopy of acantholysis in pemphigus foliaceus [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2013
We performed scanning electron microscopy of an inverted blister roof in a case of pemphigus foliaceus. The loss of intercellular adherence could be easily seen with low magnification. The acantholytic keratinocytes displayed an irregular and sometimes polygonal contour. Round cells, typically seen in light microscopy, were also observed.
de Almeida, Hiram Larangeira   +4 more
openaire   +2 more sources

Cantharidin-induced acantholysis in Darier's disease: does acantholysis initiate dyskeratosis?

open access: yesBritish Journal of Dermatology, 1994
Summary We have examined the action of cantharidin on the skin of patients with Darier's disease, and used immunohistological techniques to determine the distribution of desmosomal components, keratin intermediate filaments, and proteases in cantharidin-induced blisters.
J A, Yell, S M, Burge, D, Dean
openaire   +2 more sources

Encorafenib‐associated acantholytic dermatosis in collision with eccrine squamous syringometaplasia

open access: yes
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Francisco Meraz‐Torres   +5 more
wiley   +1 more source

Immunoadsorption of Desmoglein-3-Specific IgG Abolishes the Blister-Inducing Capacity of Pemphigus Vulgaris IgG in Neonatal Mice

open access: yesFrontiers in Immunology, 2018
Pemphigus vulgaris (PV) is a potentially life-threatening autoimmune blistering disease which is associated with autoantibodies directed against two desmosomal proteins, desmoglein (Dsg) 3 and 1.
Maxi Hofrichter   +11 more
doaj   +1 more source

Evaluating the Effect of the EAT‐Lancet Diet on Pemphigus Vulgaris Severity: Insights From a Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 7, July 2026.
ABSTRACT Background and Aims This study investigated the association between adherence to the EAT‐Lancet diet—a predominantly plant‐based, anti‐inflammatory dietary pattern—and the severity of pemphigus vulgaris (PV), a rare autoimmune blistering disease. Methods This cross‐sectional study was conducted in an Iranian population with a high incidence of
Pariya Mostafazadeh   +5 more
wiley   +1 more source

Acantholytic dyskeratotic acanthoma: case report and review of the literature

open access: yesDermatology Practical & Conceptual, 2014
Background: Focal acantholytic dyskeratosis has been described as an incidental finding and as a clinically distinct lesion. In both situations, a dimorphic histologic pattern is observed: acantholysis and dyskeratosis.
Alina Goldenberg   +2 more
doaj   +1 more source

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