Results 21 to 30 of about 2,893 (176)

A study of the correlation between acantholysis and apoptosis for the pathogenesis of pemphigus vulgaris

open access: yesVestnik Dermatologii i Venerologii, 2017
The goal of the study is to determine the particular features of pemphigus vulgaris (PV) morphogenesis and keratinocytes in the patients’ skin having morphological signs of acantholysis and apoptosis as well as changes in Langerhans cells.
YU. V. Karacheva   +2 more
doaj   +1 more source

Lichenoid lesions around the anus: An unusual site of Hailey–Hailey disease

open access: yesClinical Case Reports, 2022
The anal region is an unusual site of Hailey–Hailey disease. It manifests with lichenoid lesions with crusted erosions around the anus. It should be differentiated from condylomata acuminata, extramammary Paget disease, and bowenoid papulosis.
Fatma Hammami   +6 more
doaj   +1 more source

Sparking Fire Under the Skin? Answers From the Association of Complement Genes With Pemphigus Foliaceus

open access: yesFrontiers in Immunology, 2018
Skin blisters of pemphigus foliaceus (PF) present concomitant deposition of autoantibodies and components of the complement system (CS), whose gene polymorphisms are associated with susceptibility to different autoimmune diseases. To investigate these in
Valéria Bumiller-Bini   +7 more
doaj   +1 more source

Familial Acantholysis of Angus Calves [PDF]

open access: yesVeterinary Pathology, 1973
A disease in Angus calves was characterised by shedding of the epidermis with ulceration and inflammation of the oral mucosa and the skin of carpus, metacarpal-phalangeal joints, phalanges, coronary border, and with partial separation of the hooves.
R D, Jolly, M R, Alley, P J, O'Hara
openaire   +2 more sources

Apoptotic Pathways in Pemphigus

open access: yesDermatology Research and Practice, 2010
Pemphigus is a group of human autoimmune blistering diseases of the skin in which autoantibodies to desmosome cadherins induce loss of cell-cell adhesion (acantholysis). In addition to steric hindrance and activation of intracellular signaling, apoptosis
Meryem Bektas   +2 more
doaj   +1 more source

Development of an experimental model of pemphigus vulgaris in laboratory animals

open access: yesVestnik Dermatologii i Venerologii, 2017
Pemphigus vulgaris is a chronic autoimmune bullous disease characterized by the formation of blisters on the skin and/ or mucous tunics as a result of acantholysis.
A. A. Kubanov   +6 more
doaj   +1 more source

Pênfigo foliáceo em um eqüino Pemphigus foliaceus in a horse

open access: yesCiência Rural, 2007
Pênfigo foliáceo é uma rara afecção cutânea auto-imune que acomete várias espécies. Relata-se o caso de uma égua de quatro anos de idade, sem raça definida, apresentando áreas de alopecia, exsudação e crostas localizadas na face, região peitoral e ...
Gabriel Augusto Monteiro   +4 more
doaj   +1 more source

Pemphigus and beyond

open access: yesClinical Dermatology Review, 2021
A 23-year-old male diagnosed with pemphigus foliaceous presented with multiple asymptomatic hyperpigmented patches and plaques clinically resembling seborrheic keratoses over multiple sites on the body of 1-year duration.
Shital Poojary, Kavya Baddireddy
doaj   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond   +6 more
wiley   +1 more source

Acantholysis revisited: Back to basics

open access: yesIndian Journal of Dermatology, Venereology, and Leprology, 2013
Acantholysis means loss of coherence between epidermal cells due to the breakdown of intercellular bridges. It is an important pathogenetic mechanism underlying various bullous disorders, particularly the pemphigus group, as well as many non-blistering disorders.
Divya, Seshadri   +2 more
openaire   +2 more sources

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