Results 11 to 20 of about 2,893 (176)

A Case Report of a Patient With Recalcitrant Pemphigus Vulgaris Treated With Rituximab. [PDF]

Clin Case Rep
ABSTRACT Pemphigus vulgaris may demonstrate differential treatment responses across disease sites. In this case, cutaneous lesions responded to high‐dose corticosteroids, whereas refractory oral disease required rituximab to achieve remission, highlighting the need for individualized, multimodal therapy to achieve sustained disease control.
Kgokolo MC, Nevondo LM, Beetge M, Khammissa RAG.   +3 more
europepmc   +2 more sources

Atypical Follicular-Pigmentary Variant of Hailey-Hailey Disease: A Diagnostic Dilemma. [PDF]

Clin Case Rep
ABSTRACT Hailey–Hailey disease (HHD) is a rare autosomal dominant acantholytic dermatosis characterized by recurrent erosive plaques in intertriginous areas. Atypical presentations can resemble other acantholytic disorders, making diagnosis challenging. A 38‐year‐old male presented with recurrent pruritic lesions over flexural regions, worsened by heat
Shah S, Shrestha J, Baniya R, Bhusal M, Pradhan K, Maharjan R.   +5 more
europepmc   +2 more sources

Effective Management of Recalcitrant Hailey-Hailey Disease With Risankizumab. [PDF]

Int J Dermatol
International Journal of Dermatology, Volume 65, Issue 7, Page 1457-1459, July 2026.
Justice J, Della Porta A, Niklinska E, Miller JL.   +3 more
europepmc   +2 more sources

Paraneoplastic Pemphigus/Paraneoplastic Autoimmune Multiorgan Syndrome Associated With Castleman Disease: Multidisciplinary Management of a Rare Life-Threatening Syndrome. [PDF]

Clin Case Rep
ABSTRACT Refractory oral erosions or polymorphous eruptions should prompt evaluation for paraneoplastic pemphigus, particularly when associated with mediastinal masses. Early tumor excision, multidisciplinary care, and vigilant monitoring for bronchiolitis obliterans are essential to improve outcomes in Castleman disease–associated paraneoplastic ...
Sohail A, Evans J, Tabata M.
europepmc   +2 more sources

Endocytosis of IgG, Desmoglein 1, and Plakoglobin in Pemphigus Foliaceus Patient Skin

Frontiers in Immunology, 2019
Pemphigus foliaceus (PF) is one of the two main forms of pemphigus and is characterized by circulating IgG to the desmosomal cadherin desmoglein 1 (DSG1) and by subcorneal blistering of the skin.
Dyah A. M. Oktarina, Dyah A. M. Oktarina, Ena Sokol, Duco Kramer, Marcel F. Jonkman, Hendri H. Pas   +5 more
doaj   +1 more source

Acantholytic and Pagetoid Variant of Bowen’s Disease with Microinvasion on the Scalp of a Young Female Patient: A Case Report [PDF]

Iranian Journal of Medical Sciences, 2019
Bowen’s disease (BD) is a non-melanoma skin cancer with several histological subtypes. Herein we describe a case of a 35-year-old woman with a 4-cm diameter crusted plaque on the parietal scalp region. She had the lesion for 2 years.
Maryam Nasimi, Arghavan Azizpour, Azita Nikoo, Robabeh Abedini, Safoura Shakoei   +4 more
doaj   +1 more source

The Role of Non-Neuronal Acetylcholine in the Autoimmune Blistering Disease Pemphigus Vulgaris

Biology, 2023
The importance of acetylcholine (ACh) in keratinocyte adhesion and acantholysis has been investigated over the last three decades, particularly in the pathophysiology of autoimmune blistering dermatoses.
Delila Pouldar Foulad, Nicola Cirillo, Sergei A. Grando   +2 more
doaj   +1 more source

Keratinocyte Dissociation (Desmolysis/Acantholysis) in Ameloblastoma [PDF]

Clinics and Practice, 2020
Ameloblastoma is the only odontogenic tumor that displays diversified histomorphological features with subtypes like follicular, plexiform, acanthomatous, granular cell, clear cell, desmoplastic etc. In this paper we presented an extremely unusual presentation of ameloblastoma, which is characterized by desmolysis or acantholysis of stellate reticulum ...
Sachin C. Sarode, Gargi S. Sarode, Praveen Birur, Yaser A. Alhazmi, Shankargouda Patil   +4 more
openaire   +2 more sources

The Mechanism of Cantharidin Acantholysis

Journal of Investigative Dermatology, 1962
In an earlier paper (1), we reviewed the literature concerning eantharidin aeantholysis and commented on the theories thus far proposed to explain its production. New data were presented, and it was concluded that no adequate biochemical explanation currently exists.
Weakley, David R., Einbinder, Julia M.
openaire   +2 more sources

Blocking soluble Fas Ligand ameliorates pemphigus: PC111 efficacy in ex-vivo human pemphigus models

Frontiers in Immunology, 2023
Pemphigus is a life-threatening, chronic, autoimmune bullous disease affecting both the skin and the mucous membranes. Based on the mainstream concept that blister formation occurs upon binding of autoantibodies to their antigen proteins (desmoglein1 ...
Roberta Lotti, Roberta Lotti, Jennifer E. Hundt, Ralf J. Ludwig, Christoph M. Hammers, Brydon Bennett, Antonino Amato, Alessandra Marconi, Alessandra Marconi, Carlo Pincelli, Carlo Pincelli   +10 more
doaj   +1 more source