Results 51 to 60 of about 13,735 (206)
Change‐of‐function fibroblast growth factor receptor 3 mutations causing skeletal dysplasias
Journal of Cell Communication and Signaling, Volume 20, Issue 4, December 2026.We show that the ligands FGF1 and FGF2 elicit differential fibroblast growth factor receptor 3 (FGFR3) signaling responses and that the FGFR3 G380R and A391E mutations reshape these signaling outputs. Thus, pathogenic FGFR3 mutations found in skeletal dysplasia do not simply enhance signaling strength and should be reclassified from “gain‐of‐function ...
Tanaya Roy +4 more
wiley +1 more source
Cohen syndrome with acanthosis nigricans and insulin resistance
, 2001 Cohen syndrome is a rare genetic disorder consisting of truncal obesity, hypotonia, mental retardation, microcephalia, characteristic facial appearance and ocular anomalies.
B. Elmas +9 more
core +1 more source
Screening for Acanthosis nigricans: Analyzing the Correlation between Socio-economics and Acanthosis nigricans [PDF]
, 2005 Contemporary research pertaining to the prevalence rate of schoolchildren with a skin pigmentation condition called acanthosis nigricans demonstrates that causal factors, such as ethnicity and obesity, can make children more at-risk for obtaining this ...
Walker, Craig A.
core +2 more sources
Caspian Journal of Internal Medicine, 2021 Background: Acanthosis nigricans (AN) is a condition with an important characteristics of symmetrical areas of thickened skin with grayish brown Hyperpigmentation. The mucosa may show a papillomatous surface, with or without hyperpigmentation.
pegah Mosannen Mozafari +5 more
doaj
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 6, November 2026.This meta‐analysis of 42 studies, including 5363 women with PCOS, found that obesity was associated with more severe reproductive, androgenic, metabolic, and cardiometabolic abnormalities. Lean PCOS also carried substantial metabolic risk, supporting phenotype‐informed assessment and cardiometabolic screening regardless of BMI.
Fatema Tuz Zahura Aalpona +4 more
wiley +1 more source
HUBUNGAN KADAR RESISTIN DENGAN DERAJAT ACANTHOSIS NIGRICANS PADA REMAJA OBESITAS
, 2015 Latar Belakang. Obesitas pada anak berhubungan dengan meningkatnya risiko penyakit kardiovaskuler dan sindrom metabolik seperti resistensi insulin. Secara klinis, resistensi insulin dapat bermanifestasi sebagai munculan acanthosis nigricans.
DINI, NOVIARTI
core +2 more sources
Case Reports in Dermatology, 2019 We herein present the first case of nanoparticle albumin-bound paclitaxel (nab-paclitaxel)- and/or gemcitabine-induced scleroderma accompanied by acanthosis nigricans-like skin changes in a 54-year-old Japanese male.
Sei-ichiro Motegi +3 more
doaj +1 more source
Evaluation of androgen-dependent skin findings of polycystic ovary syndrome (PCOS)
Gynecological Endocrinology, 2022 Aim The purpose of the study was to investigate the biochemical and metabolic abnormalities related to the cutaneous characteristics of PCOS.Material–Methods Patients diagnosed with PCOS were included in the study.
Gokhan Artar +3 more
doaj +1 more source
Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.ABSTRACT Background The prevalence of consumption of sports supplements and performance enhancers has increased among the general population. While these products are intended to improve muscle growth, endurance, and performance, several dermatologic effects have been reported.
Firas F. Haddad +4 more
wiley +1 more source
Rheumatologic Manifestations of Patients With Type B Insulin Resistance
Arthritis Care &Research, Volume 78, Issue 9, Page 1195-1200, September 2026.Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya +4 more
wiley +1 more source