Results 61 to 70 of about 13,735 (206)

Será a acanthosis nigricans uma nova manifestação cutânea de infecção pelo vírus da imunodeficiência humana?

open access: yesActa Médica Portuguesa, 1997
The authors describe a clinical case of AIDS presented by three opportunistic infections (esophageal candidiasis, tuberculosis and atypical mycobacteriosis) and a dermatological manifestation--acanthosis nigricans--not described in medical literature as ...
F Maltez   +3 more
doaj   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

open access: yesiNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little   +12 more
wiley   +1 more source

Acanthosis nigricans: A flag for insulin resistance [PDF]

open access: yes, 2014
Objectives: Acanthosis nigricans refers to the velvety, black  hyperpigmentation seen in the flexures. It is a cutaneous marker for insulin resistance (IR), some metabolic disorders and rarely malignancy.
Anandan, S, Venkatswami, S
core  

Acanthosis Nigricans Associated with Morbid Obesity and Colorectal Adenocarcinoma [PDF]

open access: yes, 2012
We report a case of a morbidly obese 32-year-old man presenting with acanthosis nigricans in the setting of Duke's B adenocarcinoma of the hepatic ...
J. Li   +5 more
core   +1 more source

European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) steatotic liver disease special interest group position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction‐associated steatotic liver disease

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 3, Page 555-576, September 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disease.
Jake P. Mann   +30 more
wiley   +1 more source

Androgen Excess Disorders in Women: The Severe Insulin-Resistant Hyperandrogenic Syndrome, HAIR-AN

open access: yesThe Scientific World Journal, 2006
HAIR-AN syndrome (hyperandrogenism, insulin resistance, acanthosis nigricans) is a subset of the polycystic ovary syndrome, where the patients demonstrate severe insulin resistance.
Kristin M. Rager, Hatim A. Omar
doaj   +1 more source

Advances in FGF/FGFR Signaling: Implications for Disease and Therapy

open access: yesMedComm, Volume 7, Issue 9, September 2026.
The FGF/FGFR signaling is indispensable for the maintenance of physiological homeostasis and governs multiple biological processes, including embryonic development, bone metabolism, angiogenesis, and neurogenesis, whereas aberrant hyperactivation of this pathway drives the progression of malignancies and autoimmune disorders, including inflammatory ...
Miaoyu Song   +4 more
wiley   +1 more source

Acanthosis Nigricans [PDF]

open access: yesMayo Clinic Proceedings, 2004
Alexander K.C. Leung, C. Pion Kao
  +5 more sources

Costello Syndrome Associated With Somatic Mosaicism of Rare p.Gly13Asp HRAS Variant: Expanding the Phenotypic Spectrum

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
We report a case of a 22‐year‐old woman with predominantly cutaneous involvement in whom whole‐exome sequencing from both blood‐ and hair‐derived DNA samples identified somatic mosaicism for the rare HRAS p.Gly13Asp variant. This case expands the phenotypic spectrum of Costello syndrome and underscores the importance of multitissue genomic analysis ...
Jovan Lalosevic   +6 more
wiley   +1 more source

Unilateral Nevoid Acanthosis Nigricans on the Back: A Case Report

open access: yesActa Medica Iranica, 2019
Unilateral Nevoid Acanthosis Nigricans (UNAN) is a rare, benign, autosomal dominant form of Acanthosis Nigricans (AN), which is a disorder of keratinization. Unlike AN, the lesions of UNAN are distributed unilaterally while the histopathological findings
Mohammad Ebrahimzadeh Ardakani   +2 more
doaj   +1 more source

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