Results 71 to 80 of about 13,735 (206)

Interventions to Reduce Screen Time in Preschool‐Aged Children: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesObesity Reviews, Volume 27, Issue 9, September 2026.
ABSTRACT Background The impact of interventions aimed at reducing screen use in preschool‐aged children is unclear. This systematic review and meta‐analysis aimed to evaluate interventions to reduce screen time among preschool‐aged children and examine the characteristics of effective interventions.
Meenushree Chandrasekaran   +9 more
wiley   +1 more source

Current treatment options for acanthosis nigricans

open access: yes, 2018
Nupur U Patel,1 Catherine Roach,1 Hossein Alinia,1 William W Huang,1 Steven R Feldman1–3 1Department of Dermatology, Center for Dermatology Research, Wake Forest University School of Medicine, Winston-Salem, NC, 2Department of Pathology, Wake ...
Patel NU   +4 more
core  

Setmelanotide in Bardet‐Biedl Syndrome: A Case Report

open access: yesPediatric Dermatology, Volume 43, Issue 5, Page 1196-1199, September/October 2026.
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith   +2 more
wiley   +1 more source

Atypical Presentation of Neuropsychiatric Lupus With Acanthosis Nigricans

open access: yes, 2012
Cutaneous manifestations are commonly observed in pediatric patients with systemic lupus erythematosus. Acanthosis nigricans, however, is rarely reported, and even less often in association with neuropsychiatric manifestations of lupus erythematosus.
Lascelles, Karine   +4 more
core   +1 more source

Acanthosis nigricans: A cutaneous marker for metabolic syndrome

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth, 2019
Background: Acanthosis Nigricans (AN) is an easily identifiable dermatoses characterized by thickened, hyperpigmented plaques. Metabolic syndrome refers to a clustering of metabolic risk factors including central obesity, glucose intolerance ...
Nirali Girish Shah   +4 more
doaj   +1 more source

The Clinical Phenotype and Genetic Analysis of Monogenic Non Syndromic Obesity Caused by MC4R Gene Variation

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.
A novel MC4R mutation (c.185A > G) was identified in a 10‐year‐old girl with severe obesity and hyperinsulinemia. Retrospective analysis of 64 pediatric cases revealed that mutation location influences BMI, modulated by underlying disease status, demonstrating that the genotype–phenotype relationship in MC4R‐associated obesity is clinically context ...
Xin Li   +4 more
wiley   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue S4, Page 3-16, August 2026.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib   +3 more
wiley   +1 more source

Correlation of cutaneous manifestations with body mass index, blood glucose, and hormonal levels in patients with polycystic ovarian disease

open access: yesIndian Dermatology Online Journal, 2020
Background: Polycystic ovarian disease (PCOD) is characterized by oligo/anovulation, ultrasonographic evidence of polycystic ovaries and cutaneous features such as hirsutism, acne, acanthosis nigricans, androgentic alopecia, and signs of virilization ...
Yugal K Sharma   +3 more
doaj   +1 more source

Cutaneous clues: Malignant acanthosis nigricans and tripe palms as first signs of recurrent endometrial carcinoma

open access: yesTaiwanese Journal of Obstetrics & Gynecology
Objective: ‘Tripe palm’ is a rare cutaneous paraneoplastic syndrome characterized by velvety thickening of the palms with a ridged or rugose appearance. The condition, either on its own or in combination with acanthosis nigricans, is strongly associated ...
Da-Hsin Dzwo   +4 more
doaj   +1 more source

Severe, Malignant Acanthosis Nigricans Associated with Adenocarcinoma of the Endometrium in a Young Obese Female

open access: yesCase Reports in Dermatology, 2017
Acanthosis nigricans (AN) is a dermatopathy associated with insulin-resistance, drugs, endocrine disorders, chromosomal abnormalities (benign AN), and neoplasia (malignant AN).
Jacqueline Deen   +2 more
doaj   +1 more source

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