Results 71 to 80 of about 13,735 (206)
ABSTRACT Background The impact of interventions aimed at reducing screen use in preschool‐aged children is unclear. This systematic review and meta‐analysis aimed to evaluate interventions to reduce screen time among preschool‐aged children and examine the characteristics of effective interventions.
Meenushree Chandrasekaran +9 more
wiley +1 more source
Current treatment options for acanthosis nigricans
Nupur U Patel,1 Catherine Roach,1 Hossein Alinia,1 William W Huang,1 Steven R Feldman1–3 1Department of Dermatology, Center for Dermatology Research, Wake Forest University School of Medicine, Winston-Salem, NC, 2Department of Pathology, Wake ...
Patel NU +4 more
core
Setmelanotide in Bardet‐Biedl Syndrome: A Case Report
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith +2 more
wiley +1 more source
Atypical Presentation of Neuropsychiatric Lupus With Acanthosis Nigricans
Cutaneous manifestations are commonly observed in pediatric patients with systemic lupus erythematosus. Acanthosis nigricans, however, is rarely reported, and even less often in association with neuropsychiatric manifestations of lupus erythematosus.
Lascelles, Karine +4 more
core +1 more source
Acanthosis nigricans: A cutaneous marker for metabolic syndrome
Background: Acanthosis Nigricans (AN) is an easily identifiable dermatoses characterized by thickened, hyperpigmented plaques. Metabolic syndrome refers to a clustering of metabolic risk factors including central obesity, glucose intolerance ...
Nirali Girish Shah +4 more
doaj +1 more source
A novel MC4R mutation (c.185A > G) was identified in a 10‐year‐old girl with severe obesity and hyperinsulinemia. Retrospective analysis of 64 pediatric cases revealed that mutation location influences BMI, modulated by underlying disease status, demonstrating that the genotype–phenotype relationship in MC4R‐associated obesity is clinically context ...
Xin Li +4 more
wiley +1 more source
Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib +3 more
wiley +1 more source
Background: Polycystic ovarian disease (PCOD) is characterized by oligo/anovulation, ultrasonographic evidence of polycystic ovaries and cutaneous features such as hirsutism, acne, acanthosis nigricans, androgentic alopecia, and signs of virilization ...
Yugal K Sharma +3 more
doaj +1 more source
Objective: ‘Tripe palm’ is a rare cutaneous paraneoplastic syndrome characterized by velvety thickening of the palms with a ridged or rugose appearance. The condition, either on its own or in combination with acanthosis nigricans, is strongly associated ...
Da-Hsin Dzwo +4 more
doaj +1 more source
Acanthosis nigricans (AN) is a dermatopathy associated with insulin-resistance, drugs, endocrine disorders, chromosomal abnormalities (benign AN), and neoplasia (malignant AN).
Jacqueline Deen +2 more
doaj +1 more source

