Results 81 to 90 of about 18,511 (201)

Phenolic Profiling and Bioactivity Evaluation of Stachys aleurites Extracts: LC–ESI–MS/MS Characterization, Antioxidant Capacity, and Enzyme Inhibitory Potential

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Solvent polarity shapes the phytochemical and bioactivity profile of Stachys aleurites. Methanol extraction enriches phenolics, especially verbascoside and chlorogenic acid, and enhances antioxidant and enzyme inhibitory activities, whereas the aqueous extract shows selective metal‐chelating and BChE inhibitory potential. ABSTRACT Natural products rich
Fatma Ozlem Kargin Solmaz   +2 more
wiley   +1 more source

A randomized controlled trial of acarbose in hepatic encephalopathy

open access: yes, 2005
Background & aims: Hepatic encephalopathy in cirrhosis is contributed to by toxic products deriving from the proteolytic bacterial flora-related degradation of dietary nitrogen substances.
Guarino, Giuseppina   +8 more
core   +1 more source

Effect of Acarbose on Control of Metabolic Parameters in Patients with Diabetes Type 1

open access: yesپزشکی بالینی ابن سینا, 2012
Introduction & Objective: Acarbose is an intestinal alpha-glucosidase inhibitor that delays absorption of carbohydrates. Findings of some studies show that it has been effective in better control of blood glucose in patients with diabetes type 1.
Amir Ziaee   +4 more
doaj  

Sulfonamide‐Based 2‐Amino‐1,3,4‐Oxadiazole Derivatives as Dual Cholinesterase and Carbonic Anhydrase Inhibitors: Design, Synthesis, Kinetic Characterization, Molecular Modeling, and ADMET Evaluation

open access: yesDrug Development Research, Volume 87, Issue 6, September 2026.
ABSTRACT In this study, 12 novel sulfonamide derivatives incorporating 2‐amino‐1,3,4‐oxadiazole and 1,3‐benzazol‐2(3H)‐one scaffolds were synthesized and structurally characterized using 1H NMR, 13C NMR, and LC–MS analyses. Their inhibitory activities were evaluated against acetylcholinesterase (AChE), butyrylcholinesterase (BChE), carbonic anhydrase I
Gülnur Arslan Karahan   +4 more
wiley   +1 more source

Acarbose-Loaded PLGA Microspheres: Efficient Encapsulation and Controlled Release [PDF]

open access: yes
Acarbose, a locally administered oral anti-diabetic agent, also experiences bioavailability and controlled release difficulties. To overcome such limitations, Acarbose-loaded microspheres were designed to ensure a higher therapeutic efficacy through ...
Khanage, S. G.   +2 more
core   +1 more source

Crocus sativus (Saffron) Aqueous Extract Mediated Green Synthesis of Iron Oxide Nanoparticles and Their In Vitro and In Vivo Biological Investigations

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
The Crocus sativus (saffron) aqueous extract mediated green synthesis of iron oxide nanoparticles and their in vitro and in vivo biological investigations. ABSTRACT The present study reports the green synthesis of iron oxide nanoparticles (IONPs) using the aqueous extract of Crocus sativus (saffron) as a natural reducing and stabilizing agent, followed
Abdur Rauf   +10 more
wiley   +1 more source

Intelligent design of artificial biocatalyst for biomedical diseases

open access: yesJournal of Intelligent Medicine, Volume 3, Issue 3, Page 220-249, September 2026.
This review summarizes recent advances in the intelligent design of artificial biocatalysts for biomedical diseases. By leveraging tailored design strategies, including environment‐responsive engineering and rational/artificial intelligence‐aided optimization, these biocatalysts enable precise modulation of pathological microenvironments and targeted ...
Lijie Zhang   +3 more
wiley   +1 more source

Transfersomes as a Carrier for Transdermal Delivery of Acarbose [PDF]

open access: yes, 2008
This study was to investigate the possible influence of Acarbose on glucagons like peptide-1 release and gastric emptying in type 2 diabetic patients after mixed test meal.
Dinesh Kumar, V
core  

Evaluation of Serum Vaspin and Chemerin Levels in Type 2 Diabetic and Treated with Anti Diabetic Drugs Metformin and Acarbose in Rats [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2015
Background & Objective: The serum levels of adipose tissue hormons, Vaspin and Chemerin, alter in some disorder conditions such as diabetes. The aim of this study is to investigate the effect of two anti-diabetic drugs (Metformin and Acarbose) and their ...
Seyed Mohammad Ali Ghaffari   +3 more
doaj  

Combining Insulin Glargine with Metformin and Acarbose in Type 2 Diabetes: A Randomized Trial [PDF]

open access: yesStudies in Multidisciplinary Medical Research
This parallel triple-blind randomized controlled trial evaluated the efficacy of combining insulin glargine with metformin, acarbose, or both in managing blood sugar levels in 87 patients with uncontrolled type 2 diabetes.
Mojgan Sanjari   +6 more
doaj   +1 more source

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