Results 81 to 90 of about 16,949 (211)

Effect of Betulinic Acid on Diabetes and its Associated Complications: An Experimental Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Diabetes Mellitus (DM) is a metabolic disease characterised by elevated blood sugar levels and associated complications, such as inflammation, oxidative stress and tissue damage.
Sree Thalir Anbuchezian, Royapuram Parthasarathy Parameswari, Anitha Roy   +2 more
doaj   +1 more source

Recycling of hazelnut waste: Antidiabetic properties of soy lecithin nanoparticles and their in vitro anti‐proliferative effects in tumor cell lines

Journal of the Science of Food and Agriculture, Volume 106, Issue 9, Page 5596-5613, July 2026.
Abstract BACKGROUND Hazelnuts and foods produced using hazelnuts are consumed with pleasure, but it is important to evaluate the waste generated during hazelnut processing and determine their usage methods. RESULTS This study was conducted to determine the changes in bioactive components, bioaccessibility and antidiabetic activity of nanoparticles ...
Mehmet Ali Temiz, Emine Okumus
wiley   +1 more source

Comparison of medical resources and costs among patients with coronary heart disease and impaired glucose tolerance in the Acarbose Cardiovascular Evaluation trial

Journal of Diabetes
Background The Acarbose Cardiovascular Evaluation (ACE) trial (ISRCTN91899513) evaluated the alpha‐glucosidase inhibitor acarbose, compared with placebo, in 6522 patients with coronary heart disease and impaired glucose tolerance in China and showed a ...
Liam Mc Morrow, Frauke Becker, Ruth L. Coleman, Hertzel C. Gerstein, Lars Rydén, Stefan Schöder, Alastair M. Gray, Jose Leal, Rury R. Holman, for the ACE Study Group   +9 more
doaj   +1 more source

Evaluation of Enzyme Inhibition and Kinetic Profiles of Origanum Essential Oils on Metabolic and Central Nervous System Targets

Natural Sciences, Volume 6, Issue 3, July 2026.
The essential oils of three Origanum species were chemically characterized and evaluated for their antioxidant and enzyme inhibitory activities. The different compositions confer selective bioactivities: O. vulgare exhibits good antioxidant and α‐glucosidase inhibitory activity, O. majorana shows promising tyrosinase inhibition, and O.
Giuseppe Amato, Lucia Caputo, Laura De Martino, Daniela Grulova, Barbara Borczak, Joanna Kapusta‐Duch, Vincenzo De Feo   +6 more
wiley   +1 more source

A systematic review and meta‐analysis of the relative benefit of dual versus single oral hypoglycaemic therapy following diagnosis with type 2 diabetes (T2D)

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Introduction Achieving and sustaining target glycated haemoglobin (HbA1c) levels is fundamental in the management of type 2 diabetes (T2D). We here aimed to assess whether initial dual oral therapy outperforms monotherapy in reaching glycaemic targets in patients with treatment‐naive or early‐stage T2D.
Mairead Kelly, Sushant Saluja, Hugh Logan Ellis, Sarah Jamil, Martin B. Whyte, Adrian Heald   +5 more
wiley   +1 more source

Acarbose-Loaded PLGA Microspheres: Efficient Encapsulation and Controlled Release

Acarbose, a locally administered oral anti-diabetic agent, also experiences bioavailability and controlled release difficulties. To overcome such limitations, Acarbose-loaded microspheres were designed to ensure a higher therapeutic efficacy through ...
Khanage, S. G., Mishra , Anurag, Waghamare , Suresh   +2 more
core   +1 more source

Dual Modeling for Optimization of Corosolic Acid Extraction Conditions From Lagerstroemia speciosa Leaves Using RSM and ANN–GA

Journal of Food Process Engineering, Volume 49, Issue 7, July 2026.
Dual modeling of Lagerstroemia speciosa leaf extraction identified ethanol‐rich conditions for corosolic acid recovery. ANN–GA nominated a validated optimum at 98.3% ethanol and 106.5 min, yielding 0.974 ± 0.03 μg/mg corosolic acid with 2.3% relative error.
Seoyeon Yu, Jungshik Bae, Jaecheol Kim
wiley   +1 more source

The evolution of cyclodextrin glucanotransferase product specificity [PDF]

, 2009
Cyclodextrin glucanotransferases (CGTases) have attracted major interest from industry due to their unique capacity of forming large quantities of cyclic α-(1,4)-linked oligosaccharides (cyclodextrins) from starch.
Dijkhuizen, Lubbert; id_orcid, Leemhuis, Hans, Lubbert Dijkhuizen, Hans Leemhuis, Ronan M. Kelly, Dijkhuizen, Lubbert,, Dijkhuizen, Lubbert, Kelly, Ronan M.,, Leemhuis, Hans,, Kelly, Ronan M.   +9 more
core   +1 more source

NMR Data Analysis of Acarbose

Chinese Journal of Magnetic Resonance
Acarbose, an α-glucosidase inhibitor, has been widely used in the treatment of type-II diabetes due to its unique mechanism of action. In this study, comprehensive and accurate 1H and 13C NMR data of acarbose in DMSO-d6, including 1H NMR data of all ...
LI Yujiang, ZHAO Wei, TAO Le, LU Bohua, ZHENG Guo, ZHANG Haiyan, GUO Xiaohe, ZHAO Tianzeng   +7 more
doaj   +1 more source

Proanthocyanidin‐Rich Cranberry Extract Lowers Glycemia in Established Obesity by Delaying Glucose Absorption

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Schematic summary of the metabolic effects and proposed mechanisms of action of proanthocyanidin‐rich cranberry extract (PRCE) supplementation in mice with established diet‐induced obesity housed under thermoneutral (30°C) or cold‐exposed (10°C) conditions.
Sarra Beji, Mathilde Mouchiroud, Laura Tribouillard, Bernie Efole, Lia Perazza, Léa Favereaux, Audrey Poirier, Wandy Idris, Yves Gélinas, Thibault V. Varin, Carole Rovère, Fernando Forato Anhê, Frédéric Picard, Mathieu Laplante, André Marette, Andréanne Michaud, Alexandre Caron   +16 more
wiley   +1 more source