W pracy opisano budowę i działanie akarbozy, jak i jej wpływ na glikemię poposiłkową. Akarboza jest ważnym lekiem hamującym powstanie jawnej cukrzycy i zmniejszającym ryzyko sercowo-naczyniowe u osób ze stanem przedcukrzycowym.
Sieradzki, Jacek
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Abdul R Shihabi,1 Essam M Moussa,2 Hania Sobierajska,3 Birgit Schmidt4 1Al Ain Centre, Dubai, United Arab Emirates; 2New Jeddah Hospital, Jeddah, Saudi Arabia; 3Etihad Airways Medical Centre, Abu Dhabi, United Arab Emirates; 4Bayer Schering Pharma AG ...
Sobierajska H +3 more
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Optimization of culture medium for the cultivation of Actinoplanes sp. mutant strains and purification of acarbose: Research article [PDF]
In order to improve the production of acarbose, the fermentation medium of acarbose-producing strain Actinoplanes sp. KCTC 9161 – L14 mutant was optimized in this internship. Fractional factorial design was employ to investigate the influences of glucose,
Le, Thanh Hoang +2 more
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Base case results for dapagliflozin arm versus acarbose arm.
Base case results for dapagliflozin arm versus acarbose arm.
Hengjin Dong (398458) +5 more
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Effect of Betulinic Acid on Diabetes and its Associated Complications: An Experimental Study [PDF]
Introduction: Diabetes Mellitus (DM) is a metabolic disease characterised by elevated blood sugar levels and associated complications, such as inflammation, oxidative stress and tissue damage.
Sree Thalir Anbuchezian +2 more
doaj +1 more source
Acarbose impairs gut Bacteroides growth by targeting intracellular glucosidases
Acarbose is a type 2 diabetes medicine that prevents dietary starch breakdown into glucose by inhibiting host amylase and glucosidase enzymes. Numerous gut species in the Bacteroides genus enzymatically break down starch and change in relative abundance ...
Haley A. Brown +6 more
doaj +1 more source
Acarbose diminishes postprandial suppression of bone resorption in patients with type 2 diabetes
Aims: The alpha-glucosidase inhibitor acarbose is an antidiabetic drug delaying assimilation of carbohydrates and, thus, increasing the amount of carbohydrates in the distal parts of the intestines, which in turn increases circulating levels of the gut ...
Hartmann, Bolette +19 more
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Effect of Acarbose on Control of Metabolic Parameters in Patients with Diabetes Type 1
Introduction & Objective: Acarbose is an intestinal alpha-glucosidase inhibitor that delays absorption of carbohydrates. Findings of some studies show that it has been effective in better control of blood glucose in patients with diabetes type 1.
Amir Ziaee +4 more
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Acarbose: A New Option in the Treatment of Ulcerative Colitis by Increasing Hydrogen Production [PDF]
Acarbose,which is clinically widely used to treat Type 2 Diabetes,is thought to act at the small intestine by competitively inhibiting enzymes that delay the release of glucose from complex carbohydrates, thereby specifically reducing post ...
Zhang, De-Qing +5 more
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Molecular insights of acarbose metabolization catalyzed by acarbose-preferred glucosidase
The clinical efficacy of the antidiabetic drug acarbose is hampered by degradation by the acarbose-preferred glucosidase (Apg) from K. grimontii TD1.
Jiwen Zhang +6 more
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