Results 71 to 80 of about 16,949 (211)

Waist‐to‐height ratio and renal dysfunction as independent correlates of low handgrip strength in patients with type 2 diabetes

open access: yesJournal of Diabetes Investigation, EarlyView.
In 1,468 patients with type 2 diabetes, central obesity (WHtR >0.5) neutralizes the protective effects of higher BMI on muscle strength. Concurrently, visceral adiposity and CKD impose an additive threat, maximizing low handgrip strength risk (aOR = 1.74). Combining WHtR and renal tracking optimizes clinical sarcopenia screening.
Shing‐Hua Chen   +4 more
wiley   +1 more source

Safety and efficacy of acarbose in the treatment of diabetes in Chinese patients

open access: yes, 2014
Ke He*, Jun-Cheng Shi*, Xiao-Ming Mao Department of Endocrinology, Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing, People's Republic of China *These authors contributed equally to this work Abstract: Acarbose is an α
Mao XM, Shi JC, He K
core  

The role of GLP-1 in the postprandial effects of acarbose in type 2 diabetes

open access: yes, 2021
Aims: The alpha-glucosidase inhibitor acarbose is believed to reduce plasma glucose by delaying hydrolysis of carbohydrates. Acarbose-induced transfer of carbohydrates to the distal parts of the intestine increases circulating glucagon-like peptide 1 ...
Hartmann, Bolette   +9 more
core   +1 more source

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler   +2 more
wiley   +1 more source

An observational study of acarbose treatment in patients with type 2 diabetes from the Middle East and Morocco

open access: yes, 2013
Abdul R Shihabi,1 Essam M Moussa,2 Hania Sobierajska,3 Birgit Schmidt4 1Al Ain Centre, Dubai, United Arab Emirates; 2New Jeddah Hospital, Jeddah, Saudi Arabia; 3Etihad Airways Medical Centre, Abu Dhabi, United Arab Emirates; 4Bayer Schering Pharma AG ...
Sobierajska H   +3 more
core  

Molecular insights of acarbose metabolization catalyzed by acarbose-preferred glucosidase

open access: yes
The clinical efficacy of the antidiabetic drug acarbose is hampered by degradation by the acarbose-preferred glucosidase (Apg) from K. grimontii TD1.
Jiwen Zhang   +6 more
core   +1 more source

Moutan Cortex Extract Mediates Diabetic Retinopathy by Blocking the ROS‑Triggered HIF‐1α/VEGF Axis in Retinal Pigment Epithelial Cells

open access: yeseFood, Volume 7, Issue 4, August 2026.
Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li   +13 more
wiley   +1 more source

A Case of Venous Tissue Dissection During Transcatheter MitraClip Surgery

open access: yesCatheterization and Cardiovascular Interventions, Volume 108, Issue 1, Page 42-45, July 1, 2026.
ABSTRACT The MitraClip system has been widely used to treat mitral regurgitation. The complications associated with MitraClip surgery typically include clip detachment and mitral valve injury. However, cases of venous tissue dissection during surgery are relatively rare.
Shumin Ouyang   +5 more
wiley   +1 more source

Long-term improvement of metabolic control by acarbose in type 2 diabetes patients poorly controlled with maximum sulfonylurea therapy

open access: yes, 2003
Background and objective: Multiple oral therapies are required long term for the majority of patients with type 2 diabetes mellitus to achieve acceptable glycaemic levels; alternatively, insulin therapy has to be initiated.
Bachmann, W   +5 more
core  

Comprehensive Chemical and Biological Evaluation of Rosa damascena Plant Parts and Industrial Residues Using FTIR‐ATR and LC–MS/MS

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Rosa damascena flowers, buds, leaves, branches, and hydrodistillation by‐products were investigated using FTIR‐ATR, LC–MS/MS, and a series of biological assays. The integrated approach highlighted the chemical diversity and bioactive potential of both plant materials and industrial processing residues, supporting their sustainable valorization ...
Burak Bayrak   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy