Results 71 to 80 of about 18,511 (201)
, 2013 Abdul R Shihabi,1 Essam M Moussa,2 Hania Sobierajska,3 Birgit Schmidt4 1Al Ain Centre, Dubai, United Arab Emirates; 2New Jeddah Hospital, Jeddah, Saudi Arabia; 3Etihad Airways Medical Centre, Abu Dhabi, United Arab Emirates; 4Bayer Schering Pharma AG ...
Sobierajska H +3 more
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FORMULATION AND EVALUATION OF ACARBOSE PELLETS BY EXTRUSION SPHERONIZATION TECHNIQUE [PDF]
, 2020 Objective: The objective of our work is to formulate and evaluate acarbose pellets for sustain drug delivery. The present study was aimed to develop sustain drug delivery system of acarbose pellets by extrusion spheronization technique using different ...
RUBY, J. JOYSA, M. R., DILIP
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Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.ZnO/CuO@amoxicillin nanocomposite, synthesized via sol–gel route, demonstrates exceptional multifunctional performance. It strongly inhibits α‐amylase and α‐glucosidase, effectively suppresses inflammation, and exhibits superior antioxidant activity surpassing ascorbic acid.
Hocine Sadam Nesrat +10 more
wiley +1 more source
Acarbose May Function as a Competitive Exclusion Agent for the Producing Bacteria
, 2023 Acarbose is a well-known microbial specialized metabolite used clinically to treat type 2 diabetes. This natural pseudo-oligosaccharide (PsOS) shows potent inhibitory activity toward various glycosyl hydrolases, including α-glucosidases and α-amylases ...
Samuel Tanoeyadi (14438266) +9 more
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First Report on the Phytochemical and Pharmacological Properties of Hedysarum yilmazunalii
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.Hedysarum yilmazunalii was collected from Erzincan, Türkiye. The leaf, stem, and root parts were then used for methanolic extraction. The extracts were analyzed for their phytochemical composition by LC–MS/MS and tested for antioxidant, enzyme inhibitory, and antiproliferative activities.
Etem Osma +7 more
wiley +1 more source
Molecular insights of acarbose metabolization catalyzed by acarbose-preferred glucosidase
The clinical efficacy of the antidiabetic drug acarbose is hampered by degradation by the acarbose-preferred glucosidase (Apg) from K. grimontii TD1.
Jiwen Zhang +6 more
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Effect of Betulinic Acid on Diabetes and its Associated Complications: An Experimental Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: Diabetes Mellitus (DM) is a metabolic disease characterised by elevated blood sugar levels and associated complications, such as inflammation, oxidative stress and tissue damage.
Sree Thalir Anbuchezian +2 more
doaj +1 more source
Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.Citrus hystrix DC. (kaffir lime) peel was dried and subjected to ethanolic extract. The GC‐MS analysis showed the presence of significant phyto‐ingredients. Pharmacokinetic and ADMET filters were applied to major constituents, and molecular docking, Gene Ontology (GO), and KEGG pathway enrichment analyses on mechanistic plausibility were also performed.
Malathy Soundara Rajan +2 more
wiley +1 more source
Acarbose impairs gut Bacteroides growth by targeting intracellular glucosidases
mBioAcarbose is a type 2 diabetes medicine that prevents dietary starch breakdown into glucose by inhibiting host amylase and glucosidase enzymes. Numerous gut species in the Bacteroides genus enzymatically break down starch and change in relative abundance ...
Haley A. Brown +6 more
doaj +1 more source