Results 51 to 60 of about 19,411 (194)
Synthetic and Systems Biotechnology, 2019 The α-glucosidase inhibitor acarbose is produced in large-scale by strains derived from Actinoplanes sp. SE50 and used widely for the treatment of type-2 diabetes. Compared with the wild-type SE50, a high-yield derivative Actinoplanes sp.
Huixin Xie +4 more
doaj +1 more source
Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.This review firstly summarizes the update of meroterpenoids from February 2020 to December 2025 by applying a new classification method based on twelve key non‐terpene precursors. ABSTRACT Meroterpenoids are a class of hybrid natural products, biosynthesized from terpenoid fragments and non‐terpenoid precursors, exhibiting a wide range of biological ...
Yuqian Tang +6 more
wiley +1 more source
, 2009 Adipose tissue secretes biologically active mediators is adipokines. We: evaluate the effect of pioglitazone and acarbose oil adipokines and vascular remodelling markers during in oral glucose tolerance test (OGTT). Height and body weight, BMI, glycemic:
R. Mereu +10 more
core +2 more sources
Clinical Case Reports, Volume 14, Issue 11, November 2026.ABSTRACT Immune checkpoint inhibitors (ICIs) may cause rare life‐threatening ICI‐associated diabetes mellitus. We report a 60‐year‐old Chinese male with pre‐existing type 2 diabetes who developed toripalimab‐induced diabetic ketoacidosis after 3 treatment cycles. He also had toripalimab‐related hyperthyroidism.
Lingfen Zeng, Jieming Sun
wiley +1 more source
Acarbose-Loaded PLGA Microspheres: Efficient Encapsulation and Controlled Release [PDF]
Acarbose, a locally administered oral anti-diabetic agent, also experiences bioavailability and controlled release difficulties. To overcome such limitations, Acarbose-loaded microspheres were designed to ensure a higher therapeutic efficacy through ...
Khanage, S. G. +2 more
core +1 more source
Green route for efficient synthesis of metal complexes of 4-bromo-2-((E)-((2-hydroxyphenyl)imino)methyl)-6-((E)-(3-nitrophenyl)diazenyl)phenol and its anti-hyperglycemia, anticancer and antimicrobial assessment [PDF]
Journal of the Serbian Chemical SocietyThe world is battling cancer and diabetes, prompting global research into effective drugs. Studies show coordination compounds, especially substituted salicylaldehydes, exhibit strong biological activity, which increases when treated with amines.
Sakhare Kuldeep B. +3 more
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 11, November 2026.The study investigated the phytochemical composition of Vachellia tortilis subsp. raddiana leaf and gum extracts using HPLC‐DAD‐ESI‐MS/MS and evaluated their antioxidant and antidiabetic activities. The leaf extract showed a higher content of phenolic and flavonoid compounds and exhibited promising antioxidant and α‐amylase inhibitory activities ...
Douae Taha +7 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 11, November 2026.Development and evaluation of a rationally designed polyherbal formulation, highlighting its phytochemical properties, antioxidant activities, enzyme‐inhibitory effects, and antidiabetic and antihyperlipidemic potential in alloxan‐induced diabetic mice.
Md. Shakil Ahmed +6 more
wiley +1 more source
Antidiabetic Activity of an Ayurvedic Formulation Chaturmukha Rasa: A Mechanism Based Study
Journal of Pharmacopuncture, 2019 Objectives: The objective of this study was to evaluate antidiabetic activity of Chaturmukha rasa based on streptozotocin induced diabetes model, alpha amylase inhibitory activity, alpha Glucosidase inhibitory activity and inhibition of sucrase ...
Akansha Sharma +4 more
doaj +1 more source
Microbial Cell Factories, 2022 Background Acarbose, as an alpha-glucosidase inhibitor, is widely used clinically to treat type II diabetes. In its industrial production, Actinoplanes sp. SE50/110 is used as the production strain.
Zhenxin Li +6 more
doaj +1 more source