Results 21 to 30 of about 9,228,267 (373)

Accelerated biological aging in COVID-19 patients

Nature Communications, 2022
Chronological age is a risk factor for SARS-CoV-2 infection and severe COVID-19. Previous findings indicate that epigenetic age could be altered in viral infection. However, the epigenetic aging in COVID-19 has not been well studied.
Xue Cao, Wenjuan Li, Ting Wang, Dongzhi Ran, V. Davalos, Laura Planas-Serra, A. Pujol, M. Esteller, Xiaolin Wang, Huichuan Yu   +9 more
semanticscholar   +1 more source

Evidence for accelerated aging in mammary epithelia of women carrying germline BRCA1 or BRCA2 mutations

Nature Aging, 2021
During aging in the human mammary gland, luminal epithelial cells lose lineage fidelity by expressing markers normally expressed in myoepithelial cells.
Sundus F. Shalabi, M. Miyano, R. Sayaman, Jennifer C. Lopez, Tiina Jokela, Michael E. Todhunter, S. Hinz, J. Garbe, M. Stampfer, K. Kessenbrock, Victoria E. Seewaldt, Mark A. LaBarge   +11 more
semanticscholar   +1 more source

Menopause accelerates biological aging [PDF]

Proceedings of the National Academy of Sciences, 2016
Significance Within an evolutionary framework, aging and reproduction are intrinsically linked. Although both laboratory and epidemiological studies have observed associations between the timing of reproductive senescence and longevity, it is not yet known whether differences in the age of menopause are reflected in biomarkers of aging. Using
Levine, Morgan E, Lu, Ake T, Chen, Brian H, Hernandez, Dena G, Singleton, Andrew B, Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E, Quach, Austin, Kusters, Cynthia DJ, Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E, Widschwendter, Martin, Ritz, Beate R, Absher, Devin, Assimes, Themistocles L, Horvath, Steve   +18 more
openaire   +6 more sources

Association of History of Psychopathology With Accelerated Aging at Midlife

JAMA psychiatry, 2021
Key Points Question Is psychopathology associated with accelerated aging at midlife? Findings In this population-representative birth cohort study of 1037 individuals followed up to age 45 years, a history of psychopathology was associated with a faster ...
Jasmin Wertz, A. Caspi, Antony Ambler, J. Broadbent, R. Hancox, H. Harrington, Sean Hogan, R. Houts, Joan H. Leung, R. Poulton, S. Purdy, S. Ramrakha, L. Rasmussen, Leah S. Richmond-Rakerd, P. Thorne, G. Wilson, T. Moffitt   +16 more
semanticscholar   +1 more source

The effect of water potential and deterioration on some indices of germination and biochemical of linseed (Linum usitatissimum Var. Norman) seed at different temperatures [PDF]

علوم و فناوری بذر ایران, 2020
Germination is one of the most sensitive stages of plant life, which is affected by various environmental factors such as temperature and humidity.
Ali Hoseinipoor, Alireza Yadavi, Hamidreza Balouchi, َAli Moradi   +3 more
doaj   +1 more source

Recognition and Diagnosis Method of Accelerated Aging of Lithium-Ion Battery Based on Logistic Regression

World Electric Vehicle Journal, 2021
Aiming at the accelerated aging problem that may occur during the use of high specific energy lithium-ion batteries, this article proposes a method to judge the accelerated aging of lithium-ion batteries.
Naipeng Zou, Caiping Zhang, Yubin Wang, Linjing Zhang   +3 more
doaj   +1 more source

Segmental aging underlies the development of a Parkinson phenotype in the AS/AGU rat [PDF]

, 2016
There is a paucity of information on the molecular biology of aging processes in the brain. We have used biomarkers of aging (SA β-Gal, p16Ink4a, Sirt5, Sirt6, and Sirt7) to demonstrate the presence of an accelerated aging phenotype across different ...
Khojah, Sohair M., McGuinness, Dagmara, Payne, Anthony P., Shields, Paul G.   +3 more
core   +2 more sources

Non cell autonomous upregulation of CDKN2 transcription linked to progression of chronic hepatitis C disease [PDF]

, 2013
Chronic hepatitis C virus infection (C-HC) is associated with higher mortality arising from hepatic and extrahepatic disease. This may be due to accelerated biological aging; however, studies in C-HC have thus far been based solely on telomere length as ...
Barclay, Stephen, McGuinness, Dagmara, McLauchlan, John, Mills, Peter R., Patel, Arvind H., Robinson, Mark W., Shiels, Paul G., Swann, Rachael   +7 more
core   +2 more sources

Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice

Aging Cell, 2020
Senescent cells accumulate with age in vertebrates and promote aging largely through their senescence‐associated secretory phenotype (SASP). Many types of stress induce senescence, including genotoxic stress.
Matthew J. Yousefzadeh, J. Zhao, Christina Bukata, Erin A. Wade, S. McGowan, Luise A Angelini, Michael P. Bank, Aditi U. Gurkar, Collin A McGuckian, Mariah F Calubag, Jonathan I Kato, C. Burd, P. Robbins, L. Niedernhofer   +13 more
semanticscholar   +1 more source

Experimental research on accelerated aging of solid propellant under alternating temperature

FirePhysChem, 2022
The storage environment of solid rocket motor charge is always alternating. In order to study its effect on the performance of solid rocket motor charge, the accelerated aging experiments under different temperature range, temperature change period and ...
Yufeng Wang, Gaochun Li, Jinfei Li, Yundong Xiao, Zhuqing Liu, Kai Qu   +5 more
doaj   +1 more source