Results 91 to 100 of about 45,082 (299)

Creep Behaviour of Modified Mar-247 Superalloy

Archives of Metallurgy and Materials, 2016
The paper presents the results of analysis of creep behaviour in short term creep tests of cast MAR-247 nickel-based superalloy samples made using various modification techniques and heat treatment.
Cieśla M., Mańka M., Binczyk F., Gradoń P.   +3 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

The viscoelastic behavior of a composite in a thermal environment [PDF]

A proposed method for the accelerated predictions of modulus and life times for time dependent polymer matrix composite laminates is presented. The method, based on the time temperature superposition principle and lamination theory, is described in ...
Brinson, H. F., Griffith, W. I., Morris, D. H., Yeow, Y. T.   +3 more
core   +1 more source

Microstructural modelling of creep crack growth from a blunted crack [PDF]

, 1998
The effect of crack tip blunting on the initial stages of creep crack growth is investigated by means of a planar microstructural model in which grains are represented discretely. The actual linking-up process of discrete microcracks with the macroscopic
Giessen, E. van der,, Onck, P.R.,
core  

Interplay between shear loading and structural aging in a physical gel

, 2009
We show that the aging of the mechanical relaxation of a gelatin gel exhibits the same scaling phenomenology as polymer and colloidal glasses. Besides, gelatin is known to exhibit logarithmic structural aging (stiffening). We find that stress accelerates
C. Caroli, L. C. E. Struik, O. Ronsin, S. Kutter, T. Baumberger, V. Normand   +5 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Nonlinear Creep Constitutive Model of Rock Considering Hardening Effect

Geofluids
The creep of rock is a complex mechanical phenomenon driven by internal stress adjustment and the interplay between hardening and damage effects. To precisely capture the nonlinearity of rock creep and the law of accelerated deformation, a hardening ...
Dipeng Zhu, Zhiyong Hu, Shuguang Zhang, Wei Qiu, Yijie Wang, Donglan Chen, Fan Mingzhuo, Shutian Zhao, Ye Sun, Wenbo Liu   +9 more
doaj   +1 more source

Creep Mechanics of the High-Stress Soft Rock under Grade Unloading

Advances in Civil Engineering, 2020
In order to study the creep behavior of deep soft rock, gritstone was chosen as the research subject, and a rock triaxial rheometer (Rock 600-50) and acoustic emission (AE) system (SH-II) were used to carry out the grade unloading confining pressure ...
Shunjie Huang, Xiangrui Meng, Guangming Zhao, Yingming Li, Gang Liu, Chunliang Dong, Xiang Cheng, Wensong Xu, Chongyan Liu, Jun Zhou   +9 more
doaj   +1 more source

Dust Ejection from Planetary Bodies by Temperature Gradients: Laboratory Experiments

, 2011
Laboratory experiments show that dusty bodies in a gaseous environment eject dust particles if they are illuminated. We find that even more intense dust eruptions occur when the light source is turned off.
Balme, Blum, Brauer, Brüche, Calvet, Ciesla, Dennis Reiss, Dominik, Einstein, Gerhard Wurm, Greeley, Jozef Klačka, Kantorovich, Knudsen, Kocifaj, Kocifaj, Mamajek, Maxwell, Miroslav Kocifaj, Muntz, Olofsson, Paraskov, Reiss, Reynolds, Rohatschek, Ryan, Sicilia-Aguilar, Takeuchi, Teiser, Thomas, Thorben Kelling, Weidenschilling, Wood, Wurm, Wurm, Wurm, Wurm, Zheng   +37 more
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source