Results 41 to 50 of about 44,930 (304)

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Experimental Study on Creep Characteristics and Mechanisms of Wenzhou Soft Soil

Journal of Marine Science and Engineering
This study investigates the creep behavior of Wenzhou marine soft soil through 1D and triaxial creep tests, revealing that the secondary consolidation coefficient initially increases then stabilizes with stress level, decreases with OCR, increases with ...
Yongwei Chen, Yi Shi, Junju Qiu, Wei Qin, Zhijin Zhou, Guoxiang Peng, Kun Lou, Yuanyuan Liu   +7 more
doaj   +1 more source

Influence of shear stress applied during flow stoppage and rest period on the mechanical properties of thixotropic suspensions [PDF]

, 2008
We study the solid mechanical properties of several thixotropic suspensions as a function of the shear stress history applied during their flow stoppage and their aging in their solid state.
G. Ovarlez, G. Ovarlez, Guillaume Ovarlez, P. Coussot, Q. D. Nguyen, R. G. Larson, W. B. Russel, Xavier Chateau   +7 more
core   +5 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Study on symmetric creep model based on creep curves and parametric sensitivity analysis

Meitan kexue jishu
In order to obtain the creep characteristics of the surrounding rock of the Dianzhong water diversion tunnel and to study the long-term stability of the surrounding rock of the tunnel, a fully automated triaxial developed by Wuhan Institute of ...
Wenbo LIU, Shuguang ZHANG, Xiang HUANG, Yipin LIU   +3 more
doaj   +1 more source

Numerical Simulation of Non-Stationary Parameter Creep Large Deformation Mechanism of Deep Soft Rock Tunnel

Applied Sciences, 2022
The accelerated creep plays an important role in the disasters of soft-rock tunnels under high stress. However, most of previous studies only involved attenuation creep and uniform creep.
Jiancong Xu, Haiyang Wen, Chen Sun, Chengbin Yang, Guorong Rui   +4 more
doaj   +1 more source

Modeling afterslip and aftershocks following the 1992 Landers earthquake [PDF]

, 2007
One way to probe the rheology of the lithosphere and fault zones is to analyze the temporal evolution of deformation following a large earthquake. In such a case, the lithosphere responds to a known stress change that can be assessed from earthquake slip
Amelung, Amitrano, Blanpied, Bock, Bodin, Bosl, Bouchez, Chester, Cocks, Cruden, Deng, Dieterich, Dieterich, Dragert, Fialko, Fialko, Goldberg, Gordon, Gross, H. Perfettini, Hardebeck, Hardebeck, Hauksson, Hearn, Hsu, Hsu, Hudnut, J.-P. Avouac, Johnson, King, Lachenbruch, Langbein, Lapusta, Liu, Lockner, Marone, Marone, Massonnet, Miyazaki, Montési, Nelder, Okada, Peltzer, Peltzer, Perfettini, Perfettini, Perfettini, Perfettini, Perfettini, Pollitz, Pollitz, Pollitz, Press, Rice, Rice, Rubin, Rubin, Ruina, Sauber, Sauber, Savage, Savage, Savage, Savage, Scholz, Scholz, Shen, Smith, Stein, Wessel, Zweck   +70 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Non-metallic brush seals for gas turbine bearings [PDF]

, 2004
A non-metallic brush seal has been developed as an oil seal for use in turbomachinary. Traditionally labyrinth-type seals with larger clearances have been used in such applications. Labyrinth seals have higher leakage rates and can undergo excessive wear
Akşit, Mahmut Faruk, Bhate, Nitin, Demiroğlu, Mehmet, Kizil, Huseyin, Thermos, Anthony C.   +4 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source