Results 41 to 50 of about 1,072,172 (308)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Preliminary Evaluation of the Impact of Sustained Overvoltage on Low Voltage Electronics-Based Equipment

Energies, 2022
Low voltage devices connected to public electricity supply networks can be subjected to a wide range of voltage quality, including sustained overvoltage.
Jason David, Philip Ciufo, Sean Elphick, Duane Robinson   +3 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

LIFETIME ESTIMATION FROM ACCELERATED RELIABILITY TESTING USING FINITE ELEMENTS ANALYSIS [PDF]

Fiabilitate şi Durabilitate, 2013
The paper is focused at the study of the reliability and of the lifetime of ball bearings,using reliability accelerated testing. The main objectives of this paper are: the estimation of thelifetime and reliability of ball bearings.
Sebastian Marian ZAHARIA, Ionel MARTINESCU   +1 more
doaj  

Probabilistic Fatigue Life Prediction of Dissimilar Material Weld Using Accelerated Life Method and Neural Network Approach

Computation, 2019
Welding alloy 617 with other metals and alloys has been receiving significant attention in the last few years. It is considered to be the benchmark for the development of economical hybrid structures to be used in different engineering applications.
Hafiz Waqar Ahmad, Jeong Ho Hwang, Kamran Javed, Umer Masood Chaudry, Dong Ho Bae   +4 more
doaj   +1 more source

Operating channel temperature in GaN HEMTs: DC versus RF accelerated life testing

Microelectronics and reliability, 2015
Channel temperature is a key parameter for accelerated life testing in GaN HEMTs. It is assumed that self-heating is similar in RF and DC operations and that DC test results can be applied to RF operation.
J. Pomeroy, M. Uren, B. Lambert, Martin Kuball   +3 more
semanticscholar   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Pendugaan Umur Simpan Minuman Sari Buah Sirsak (Annona Muricata L.) Berdasarkan Parameter Kerusakan Fisik dan Kimia dengan Metode Accelerated Shelf Life Testing (ASLT)

Industria: Jurnal Teknologi dan Manajemen Agroindustri, 2015
Abstrak Penelitian ini bertujuan untuk memperoleh informasi umur simpan dari minuman sari buah sirsak yang dihasilkan unit usaha ABEC berdasarkan kerusakan fisik dan kimia dengan metode Accelerated Shelf Life Testing (ASLT) dengan model persamaan ...
Subarkah Arif, Susinggih Wijana, Arie Febrianto Mulyadi   +2 more
doaj  

Validating Accelerated Shelf Life Testing Methodology for Predicting Shelf Life in High-Pressure-Processed Meat Products

Applied Sciences
The shelf life of meat products is a critical factor in ensuring both consumer safety and product quality. Traditional methods for determining shelf life are labor-intensive and time-consuming, making it challenging for manufacturers to adapt to market ...
Athina Ntzimani, Maria Tsevdou, Evangelos Andrianos, Dimitrios Gounaris, Theodosios Spiliotopoulos, Petros Taoukis, Maria C. Giannakourou   +6 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source