Results 51 to 60 of about 9,684,773 (259)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

ACCELERATED LIFE TESTING WITH AN UNDERLYING THREE-PARAMETER WEIBULL MODEL [PDF]

open access: yes, 2010
The main objective of life testing is to obtain information concerning failure. This information should then be used in order to quantify reliability, improve product reliability, and to determine whether safety and reliability goals are being met.
Souza Jr., Daniel I. de   +1 more
core   +1 more source

Pendugaan Umur Simpan Minuman Sari Buah Sirsak (Annona Muricata L.) Berdasarkan Parameter Kerusakan Fisik dan Kimia dengan Metode Accelerated Shelf Life Testing (ASLT)

open access: yesIndustria: Jurnal Teknologi dan Manajemen Agroindustri, 2015
Abstrak Penelitian ini bertujuan untuk memperoleh informasi umur simpan dari minuman sari buah sirsak yang dihasilkan unit usaha ABEC berdasarkan kerusakan fisik dan kimia dengan metode Accelerated Shelf Life Testing (ASLT) dengan model persamaan ...
Subarkah Arif   +2 more
doaj  

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Validating Accelerated Shelf Life Testing Methodology for Predicting Shelf Life in High-Pressure-Processed Meat Products

open access: yesApplied Sciences
The shelf life of meat products is a critical factor in ensuring both consumer safety and product quality. Traditional methods for determining shelf life are labor-intensive and time-consuming, making it challenging for manufacturers to adapt to market ...
Athina Ntzimani   +6 more
doaj   +1 more source

The Evaluation of shelf life of Arabica mixed coffee drinks using accelerated shelf life testing method.

open access: yesCoffee and Cocoa Research Journal, 2020
Arabica coffee drinks in this study were made from three parts of coffee beans are cascara, which is the skin of coffee fruit; green coffee beans; and roasted coffee beans.
Laras Cempaka
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Theoretical and experimental researches using accelerated life testing in aerospace industry

open access: yes, 2009
Engineers in the manufacturing industries have used accelerated life test (ALT) experiments for many decades. The purpose of ALT experiments is to acquire reliability information quickly.
Zaharia, Sebastian   +3 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

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