Results 91 to 100 of about 395,934 (297)
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Multi-axis Response of a Thermal Convection-based Accelerometer
A thermal convection-based accelerometer was fabricated, and its characteristics were analyzed in this study. To understand the thermal convection of the accelerometer, the Grashof and Prandtl number equations were analyzed.
Jae Keon Kim +4 more
doaj +1 more source
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
This study examines vectorized programming for finite impulse response image filtering. Finite impulse response image filtering occupies a fundamental place in image processing, and has several approximated acceleration algorithms.
Yoshihiro Maeda +2 more
doaj +1 more source
We develop a tractable sticky price model in which the fraction of price changesevolves endogenously over time and, consistent with the evidence, increases with inflation. Because we assume that firms sell multiple products and choose how many, but not which, prices to adjust in any given period, our model admits exact aggregation and reduces to a one ...
Blanco, Andrés +3 more
openaire +2 more sources
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Acceleration of the Extreme Sea Level Rise Along the Chinese Coast
Using high‐frequency tide gauge observations from 1980 to 2017, we analyzed changes in extreme sea levels (ESLs) along the Chinese coast to examine whether extreme sea‐level rise acceleration could be observed.
Jianlong Feng +5 more
doaj +1 more source
CERN Yellow Reports: School Proceedings, Vol 1 (2017): Proceedings of the CAS-CERN Accelerator School on Accelerators for Medical ...
openaire +3 more sources
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Accelerated Motions of a Fish-Like Foil from Impulsive Starts to Terminal States
It is presented through numerical analysis that accelerated motions of a two-dimensional fish-like foil by fluid forces can be modeled from impulsive starts to terminal states.
Youichi OGATA, Tsuyoshi OGASAWARA
doaj +1 more source

