Results 91 to 100 of about 1,486,900 (338)
This paper focuses on the dynamic responses of a metro train−bridge system under train-braking. Experiments were performed on the elevated Metro Line 21 of Guangzhou (China).
Xuhui He+4 more
doaj +1 more source
Muon Acceleration in Cosmic-ray Sources
Many models of ultra-high energy cosmic-ray production involve acceleration in linear accelerators located in Gamma-Ray Bursts magnetars, or other sources.
Antchev+21 more
core +1 more source
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho+11 more
wiley +1 more source
In seinem Essay fordert Fisher eine «Management-Akzeleration», deren Aufgabe nicht ist, seine Mitarbeiter_innen «mit tausend Kleinigkeiten zu überhäufen», sondern einen Raum zum Denken zu schaffen. Der Ruf nach einer Akzeleration zielt darauf, das Management-Konzept aus der Geiselhaft des neoliberalen Managerialismus zu lösen.
openaire +3 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
THE ACCELERATING UNIVERSE [PDF]
In this article we review the discovery of the accelerating universe using type Ia supernovae. We then outline ways in which dark energy - component that causes the acceleration - is phenomenologically described. We finally describe principal cosmological techniques to measure large-scale properties of dark energy.
openaire +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
The latest studies of the 30-second sit-to-stand (30-STS) test aim to describe it by employing kinematic variables, muscular activity, or fatigue through electromyography (EMG) instead of a number of repetitions.
Cristina Roldán Jiménez+3 more
doaj +1 more source
Accelerator Modeling with MATLAB Accelerator Toolbox [PDF]
This paper introduces Accelerator Toolbox (AT) - a collection of tools to model storage rings and beam transport lines in the MATLAB environment. The objective is to illustrate the flexibility and efficiency of the AT-MATLAB framework. The paper discusses three examples of problems that are analyzed frequently in connection with ring-based synchrotron ...
openaire +2 more sources