Results 21 to 30 of about 53,047 (263)
Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, 2009 The production of highly energetic beams of both electrons and ions is a major part of the experimental programme at the Central Laser Facility (CLF), STFC Rutherford Appleton Laboratory. Every year sees a significant number of experiments done in both areas. This has been complemented by theoretical studies that have been carried out at the CLF and UK
Norreys, P, Robinson, A, Trines, R
openaire +3 more sources
What can cosmic-ray knees reveal about source populations?
Astronomy & AstrophysicsContext. Breaks in the cosmic-ray (CR) flux spectrum encode information on the properties of CR accelerator populations producing the observed flux.
Falalaki Myrto, Pavlidou Vasiliki
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Very high-energy gamma rays from ultra-fast outflows
Astronomy & AstrophysicsContext. Ultra-fast outflows (UFOs) from active galactic nuclei (AGNs) are expected to lead to the formation of sub-relativistic strong shocks expanding in a dense, circumnuclear medium, and thus have the potential to be efficient particle accelerators ...
Le Nagat Neher B. +3 more
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Solar-Terrestrial Physics, 2021 The paper addresses the problem of acceleration of particles in a constant, uniform magnetic field of magnitude B and a uniform electric field perpendicular to it, which slowly increases with time.
G.N. Kichigin
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FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Astronomy & AstrophysicsContext. Magnetic reconnection is an explosive process that accelerates particles to high energies in Earth’s magnetosphere, offering a unique natural laboratory to study this phenomenon. Aims.
Reisinger N., Bacchini F.
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Universe, 2023 Based on the expected population of core collapse supernova remnants and the huge number of detected pulsars in the Galaxy, still representing only a fraction of the real population, pulsar wind nebulae are likely to constitute one of the largest classes
Barbara Olmi
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The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source