Results 51 to 60 of about 199,344 (312)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Dynamic measurements to assess stress levels on buried hydraulic structures
Water ScienceOld masonry structures have a very special nature that require periodical inspection and evaluation programs. The problem becomes more sophisticated when dealing with vital buried hydraulic structures under continuous functional operation while bearing ...
A. M. Anwar, A. S. Hashad, M. Omar
doaj +1 more source
Regenerative Medicine and Responsible Research and Innovation: Proposals for a Responsible Acceleration to the Clinic [PDF]
Regenerative Medicine, 2017 This paper asks how regenerative medicine can be examined through the 'responsible research and innovation' (RRI) approach which has been developed over the past decade. It describes the drivers to the development of RRI, and then argues for the need to understand innovation itself through drawing on social science analysis rooted in science and ...
openaire +3 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Implications of Site Specific Response Analysis
, 2018 Definition of design earthquake characteristics, more specifically uniform hazard acceleration response spectrum, on the ground surface is the primary component for performance based design of structures and assessment of seismic vulnerabilities in urban
Ansal, Atilla +5 more
core +1 more source
Shaking table tests on topographic effects of circular-arc valleys
Yantu gongcheng xuebaoAs a typical locally irregular topography, the valley can change the seismic properties within the local site, which is usually called the topographic effects.
ZHANG Zhongjie 1, YU Haitao 2, SONG Yi 3, LIU Shu 1, WANG Zhikun 3
doaj +1 more source
The Characteristics of Seismic Response on Hard Interlayer Sites
Advances in Civil Engineering, 2020 Based on the engineering geological data of a nuclear power plant site, nine engineering geological profiles were created with hard interlayers of different thicknesses.
Jie Su +7 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Analysis of RMS Acceleration Response Spectrum for Random Pedestrian Loads
, 2011 Pedestrian loads are affected by such uncertain parameters as walking step frequency, step length, dynamic load factors and phases of harmonic components, which lead to the uncertainties of structural response.
Yi Jie Shen, Zhi Gang Song, Jie Song
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An Experiment Monitoring Signals of Coal Bed Simulation under Forced Vibration Conditions
Shock and Vibration, 2015 An experiment simulating coal seam under forced vibration conditions was conducted. Acceleration response and microseism signal during the experiment were collected and analyzed.
Chengwu Li +5 more
doaj +1 more source