Results 91 to 100 of about 55,376 (285)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Vertex Accentuation in Female Pattern Hair Loss in Asians
Siriraj Medical Journal, 2016 Background: The most common cause of hair loss seen in women is female pattern hair loss (FPHL), also known as female androgenetic alopecia. It affects the central part of the scalp, but spares the frontal hairline.
Chavalit Supsrisunjai +1 more
doaj +2 more sources
Rise and fall of vowel length in Slavic
Rasprave Instituta za Hrvatski Jezik i Jezikoslovlje, 2018 My observation that Mate Kapović’s ideas about Slavic accentuation lack a chronological perspective has evoked a furious reaction (Kortlandt 2016b: 478f., Kapović 2017).
Frederik Kortlandt
doaj +1 more source
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source
Miscellaneous remarks on Balto-Slavic accentuation [PDF]
, 2010 The highly successful conference on Balto-Slavic accentology organized by Mate Kapovic and Ranko Matasovic has given much food for thought. It has clarified the extent of fundamental disagreements as well as established areas of common interest where the
Kortlandt, Frederik H. H.
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Text underlay in Marguerite of Austria's chanson album Brussels 228 [PDF]
, 1987 No abstract ...
Edwards, W.
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
THE BASIC CHARACTERISTICS OF ŠTOKAVIAN PROSODY
Fluminensia: Journal for Philological Research, 2002 This article discusses the basic characteristics of the development of Štokavian accentuation as well as the basic characteristics of contemporary accentuation of Štokavian dialect.
Josip Lisac
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