Results 41 to 50 of about 1,278 (215)

How acceptable is the use of linguistic–phonological intervention in children with cleft palate? A qualitative study in speech therapists

International Journal of Language & Communication Disorders, 2023
AbstractBackground & AimsEven though evidence for the use of linguistic–phonological intervention approaches in children with a cleft (lip and) palate (CP±L) is still limited, these approaches are being used by speech–language pathologists (SLPs) to treat active or compensatory cleft speech disorders in clinical practice. It is, however, unknown to
Cassandra Alighieri, Kim Bettens, Greet Hens, Evelien D'haeseleer, Kristiane Van Lierde   +4 more
openaire   +2 more sources

A White Paper on Advancing Long‐Acting Therapeutics for Maternal and Pediatric Health by Bridging Gaps in Clinical Research, Access and Regulation

Clinical Pharmacology &Therapeutics, EarlyView.
As use cases for long‐acting therapeutics expand across clinical indications, there is a critical need to ensure the inclusion of women who are pregnant or breastfeeding, infants and children—populations with a historical gap in the availability of interventions already approved for use in adults.
Moherndran Archary, Robert Bies, Osei Boateng, Rachel Daley, Pierre Gashema, Mili Karina, Emily Njuguna, Sharon Nachman, Nathaniel Nkrumah, Carolyne Odula, Andrew Owen, Ethel D. Weld, Prajith Venkatasubramanian, Adeniyi Olagunju, on behalf of the Community of Practice for Long‐acting Therapeutics for Maternal and Paediatric Health, Rana Abutaima, Dorothy Akongo, Abdulnaser Alsharaa, Moherndran Archary, Shakir Atoyebi, Benoit Bestgen, Robert Bies, Osei Boateng, Andrew Butler, Edmund Capparelli, Rachel Daley, Layla Davies, Joelle Dountio, Henry Enzama, Pierre Gashema, Katila George, Dan Hawcutt, Rene Holm, Patrick Gad Iradukunda, Elodie Jambert, Mili Karina, Linda Lewis, Grace Miheso, Sebastien Morin, Andrew Morrison, Sharon Nachman, Shadia Nakalema, Emily Njunga, Nathaniel Nkrumah, Carolyne Odula‐Obonyo, Brenda Okware, Adeniyi Olagunju, Andrew Owen, Martina Penazzato, Natella Rakhmanina, Mphako Brighton Ratlabyana, Rachel Scott, Kimberly Struble, Andre‐Marie Tchouatieu, Catherine Unsworth, Prajith Venkatasubramanian, Catriona Waitt, Ethel Weld, Janine Winterbottom, Leena Zino   +59 more
wiley   +1 more source

Acceptability of minitablets in soft food. A randomised cross-over study in children

Frontiers in Pharmacology
ObjectiveTo evaluate the acceptability of placebo minitablets mixed with different volumes of soft food in children aged 6 months to 7 years.MethodsIn this UK hospital-based, randomised cross-over study, children received placebo minitablets in yoghurt ...
Jennifer C. Duncan, Rebecca Page, Janet Clark, Gabrielle Seddon, Joy Slater, Andrea Gill, Silothabo Dliso, Udeme Ohia, Nikolaos Skoutelis, Leonie Wagner-Hattler, Adrian Baumgartner, Angela Sprunk, Peter Kühl, Louise Bracken   +13 more
doaj   +1 more source

Long‐Acting Therapeutics in Pediatric Health: Bridging Innovation and Access

Clinical Pharmacology &Therapeutics, EarlyView.
Children have distinct therapeutic needs arising from age‐dependent physiology, disease epidemiology, formulation requirements, dosing considerations, and safety vulnerabilities. Despite substantial reductions in childhood mortality over the past three decades, nearly 5 million children under five died in 2023, with infectious diseases continuing to ...
Prajith Venkatasubramanian, Moherndran Archary, Daniel B. Hawcutt, Rachel Daley, Edmund Capparelli, Adeniyi Olagunju   +5 more
wiley   +1 more source

Pelleted Forage Conservation and Its Effects on Nutritional Value, Feeding Behavior, and Feed Intake in Dairy Cattle

Contemporary Agriculture
The development of a simple and economical forage conservation method suitable for local dairy farmers is essential due to the seasonal availability of forages.
Thanusan Sivalingam, Eswaran Banusha, Piriyanka Sathasivam, Ajith Jayaweera B.P.   +3 more
doaj   +1 more source

Changes in morphology, proline content, and palatability to Helix aspersa, in Plantago lanceolata in response to transplantation and polluted soil [PDF]

, 1992
High concentrations of heavy metals are a cause of stress in plants, many of which respond by accumulating high levels of the amino acid proline. Tolerant and intolerant plants may vary in their response, and this may be reflected in the palatability of ...
Lart, K.M.
core  

Studies on the Nutritional, Functional, Textural, and Sensory Characteristics of Finger and Barnyard Millet‐Incorporated Nuggets

Food Chemistry International, EarlyView.
The graphic illustrates the development of nuggets traditionally known as “wari” prepared with whole green grams and composite flour barnyard millet var. (PRJ‐1) and finger millet var. (VL‐M‐380) in a 1:1 ratio. The addition of millet significantly improved the nutritional value of nuggets, providing higher levels of protein, carbohydrates, fiber ...
Payal Chauhan, Mahesh Gupta
wiley   +1 more source

Stabilization Strategies for Catechins and Epicatechins: Recent Advances

Food Chemistry International, EarlyView.
Oxidation, epimerization, polymerization, and hydrolysis, driven by heat, pH, and oxygen, are pathways. Nano‐/microencapsulation maintains integrity with 70%–95% efficiency; biopolymer nanoparticles, starch/polysaccharide nanocarriers improve stability and dispersion. Lipid nanocarriers enhance bioavailability but raise oxidation risk.
Nuzhat Shamim, Muhammad Usman Kahlid, Mutjardah Zarrish, Ayman Furqan, Prakram Singh Chauhan, Bipindra Pandey   +5 more
wiley   +1 more source

Acceptability of placebo multiparticulate formulations in children and adults [PDF]

, 2018
Patient acceptability is an important consideration in the design of medicines for children. The aim of this study was to investigate acceptability of multiparticulates in healthy children and adults.
Orlu, M, Lopez, F, Batchelor, HK, Mistry, P, Ernest, TB, Tuleu, C, Bennett, J, Coupe, A   +7 more
core   +4 more sources

Children’s preferences among six novel moxifloxacin and linezolid-dispersible tablet formulations

IJTLD Open
BACKGROUND: Moxifloxacin (MFX) and linezolid (LZD) are key components of rifampicin-resistant TB treatment regimens. Currently, available dispersible tablet formulations of both drugs have poor palatability in children.
G. Hoddinott, H.R. Draper, N. Vanqa, S. Myeni, S. Staples, T. Sachs, M. Raffique, N. Tshethu, M. Palmer, L. Viljoen, K. Inabathina, R. Taneja, A.C. Hesseling, A.J. Garcia-Prats   +13 more
doaj   +1 more source