Results 21 to 30 of about 5,435 (258)

Acceptability of 100-mg moxifloxacin in children with rifampicin-resistant TB in three high-burden countries [PDF]

IJTLD Open
BACKGROUND: Routinely, a 400-mg tablet of moxifloxacin is used in children with rifampicin-resistant TB (RR-TB), but it has very poor acceptability. We describe the acceptability of a 100-mg dispersible moxifloxacin among children and their caregivers in
N. Suryavanshi, H.R. Draper, G. Dhumal, S. Bagchi, N.T. Castillo-Carandang, A. Marthinus, A.M.A. Cheong, A. Kinikar, M. Paradkar, A. Gupta, J.D.R. Ocampo, M.V.G. Frias IV, D.J.O. Casalme, A. Hesseling, A.J. Garcia-Prats, M. Palmer, G. Hoddinott, L. Viljoen, on behalf of the CATALYST Trial Team   +18 more
doaj   +2 more sources

Patient Acceptability and Preferences for Solid Oral Dosage Form Drug Product Attributes: A Scoping Review [PDF]

Patient Preference and Adherence
Brett Hauber,1 Mark V Hand,2 Bruno C Hancock,3 Joseph Zarrella,3 Ljiljana Harding,4 Michaela Ogden-Barker,5 Amy S Antipas,3 Stephen J Watt1 1Pfizer Inc, New York, NY, USA; 2Pfizer Ireland Pharmaceuticals, Ballintaggart, Cork, Ringaskiddy, Ireland ...
Hauber B, Hand MV, Hancock BC, Zarrella J, Harding L, Ogden-Barker M, Antipas AS, Watt SJ   +7 more
doaj   +1 more source

A chewable pediatric preparation of ibuprofen is palatable and acceptable to children [PDF]

Paediatric and Neonatal Pain, 2020
AbstractThe development of palatable and acceptable analgesics for children is a major challenge. Given the majority of medications are administered orally, and children are more sensitive to and less tolerant of bitterness, novel “child‐friendly” preparations need to be developed and tested specifically in this patient population.
Steven Barnett, Aomesh Bhatt
openaire   +2 more sources

Resistant starch—An accessible fiber ingredient acceptable to the Western palate

Comprehensive Reviews in Food Science and Food Safety, 2022
Abstract Dietary fiber intakes in Western societies are concerningly low and do not reflect global recommended dietary fiber intakes for chronic disease prevention. Resistant starch (RS) is a fermentable dietary fiber that has attracted research interest.
Sarah Kate Walsh, Alice Lucey, Jens Walter, Emanuele Zannini, Elke K. Arendt   +4 more
openaire   +4 more sources

Young patients’ involvement in a composite endpoint method development on acceptability for paediatric oral dosage forms

Research Involvement and Engagement, 2023
Background In line with the European Paediatric Regulation, the European Medicines Agency (EMA) asks for investigation of a medicine’s acceptability in paediatric medicines development. A standardised acceptability testing method combining the outcome of
Sibylle Reidemeister, Begonya Nafria Escalera, Daniel Marín, Jan Balayla, Ingrid Klingmann, Viviane Klingmann   +5 more
doaj   +1 more source

Palatability and Acceptability of Flaxseed-Supplemented Foods in Children with Sickle Cell Disease

Nutrients, 2023
Omega-3 fatty acids (w3FAs) have demonstrated benefits in several inflammatory disease states; however, limited research has been conducted in sickle cell disease (SCD). While marine-based w3FAs are used, their strong odor and taste are a barrier to long-term use. Plant-based sources, especially those in whole foods, may circumvent this barrier.
Chinenye R. Dike, Jeffrey Lebensburger, Ciara Mitchell, Betty Darnell, Casey D. Morrow, Wendy Demark-Wahnefried   +5 more
openaire   +2 more sources

Dry Pet Food Flavor Enhancers and Their Impact on Palatability: A Review

Foods, 2021
Pet foods are a vital component of the global food industry. Pet food’s success depends on its acceptance by both consumers (the pets) and purchasers (the pet owners).
Shilpa S. Samant, Philip Glen Crandall, Sara E. Jarma Arroyo, Han-Seok Seo   +3 more
doaj   +1 more source

Palatable food avoidance and acceptance learning with different stressors in female rats [PDF]

Neuroscience, 2013
Stress activates the hypothalamus-pituitary-adrenal (HPA) axis leading to the release of glucocorticoids (GC). Increased activity of the HPA axis and GC exposure has been suggested to facilitate the development of obesity and metabolic syndrome. Nonetheless, different stressors can produce distinct effects on food intake and may support different ...
N-C, Liang, M E, Smith, T H, Moran
openaire   +2 more sources

Early clinical development of artemether-lumefantrine dispersible tablet: palatability of three flavours and bioavailability in healthy subjects. [PDF]

, 2010
BACKGROUND\ud \ud Efforts to ease administration and enhance acceptability of the oral anti-malarial artemether-lumefantrine (A-L) crushed tablet to infants and children triggered the development of a novel dispersible tablet of A-L.
Kaiser, Guenther, Abdunoor M Kabanywanyi, Abdulla, Salim, Kabanywanyi Abdunoor M, Salim Abdulla, Reynolds Christine, Nuortti Marja, Gunther Kaiser, Christine Reynolds, Gilbert Lefevre, Nuortti, Marja, Serge Fitoussi, Yeh Ching-Ming, Fitoussi Serge, Romain Sechaud, Marja Nuortti, Kaiser, Günther, Amuri, Baraka, Ubben, David, Yeh, Ching-Ming, Steve Pascoe, David Ubben, Abdulla Salim, Amuri Baraka, Pascoe Steve, Kaiser Günther, Lefèvre, Gilbert, Pascoe, Steve, Ching-Ming Yeh, Kabanywanyi, Abdunoor M, Baraka Amuri, Ubben David, Séchaud Romain, Reynolds, Christine, Séchaud, Romain, Fitoussi, Serge, Lefèvre Gilbert   +36 more
core   +1 more source

Evaluation of quality and acceptability of pet pasta with buffalo tripe powder [PDF]

Journal of Veterinary and Animal Sciences, 2022
The study was undertaken with the objective of optimizing the level of tripe powder in the formulary of pet pasta. Two levels of tripe powder viz., 2.5 per cent (T1 ) and five per cent (T2 ) were added in the control formulation replacing the cereal ...
R. Yazhinidev, T. Sathu, B. Sunil , V. N. Vasudevan, Naicy Thomas, Vandana Sasidharan, K.J. Arun Sankar   +6 more
doaj   +1 more source