Results 101 to 110 of about 101,683,100 (303)
Sustainable Development Through Citizens’ Participation: Reality and Perspectives
مجلة الدراسات والبحوث القانونية, 2020 The participation of all in sustainable development is a basic principle: sustainable development requires changes in behavior, awareness of everyone, participation of all in the decision-making process through participatory democracy.
Hatem Debih, Miloud Debih
doaj
Hospitals' electronic access to information needed to treat COVID-19. [PDF]
JAMIA Open, 2023 Richwine C, Everson J, Patel V.
europepmc +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Barriers to Publish in Open Access Journals According to Medical researchers
مدیریت اطلاعات سلامت, 2015 Introduction: The Open Access Movement has been one of the best ways that can facilitate information flow. One of the representations of the Open Access Movement is Open Access Journals.
Leila Khalili
doaj
Open Access to Information. Free Licenses [PDF]
Revista Română de Biblioteconomie și Știința Informării, 2017 In order to clarify perspectives that go beyond the limitations of copyright law, Law no. 8/1996 on copyright and neighbouring rights, we will address below several concepts regarding free licenses, the context in which creative licenses emerged, how to ...
Ionela Maria Bârsan
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source