Results 111 to 120 of about 101,683,100 (303)

Modelling Access Control For Healthcare Information Systems [PDF]

open access: yes, 2007
The widening use of Information Systems, which allow the collection, extraction, storage, management and search of information, is increasing the need for information security.
Ferreira, Ana   +2 more
core  

Lack of information and access to advanced treatment for Parkinson’s disease patients

open access: yesJournal of Multidisciplinary Healthcare, 2011
J Lökk1,21Department of Neurobiology, Caring Sciences and Society, The Karolinska Institute, 2Karolinska University Hospital Huddinge, Stockholm, SwedenBackground: Parkinson’s disease (PD) patients’ own knowledge and ...
Lökk J
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Access to information and oncofertility consultation for young women with breast cancer: a population-based study. [PDF]

open access: yesSci Rep, 2023
Martinet-Kosinski F   +5 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Access to research and technical information in Denmark

open access: yes, 2011
A knowledge economy has been described as one in which the generation and exploitation of knowledge has come to play the predominant part in the creation of wealth. It is not simply about pushing back the frontiers of knowledge; it is also about the more
Brown, Sheridan   +4 more
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

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