Results 111 to 120 of about 12,772,207 (302)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Meaningful and Inclusive Access to Information

JLIS.it
With the rise of Google and Wikidata as authoritative sources of information for many, with the use of generative Artificial Intelligence, such as Chat GPT, for the creation of new content, and with linked open data as the new, global means of ...
Philip Schreur
doaj   +1 more source

A new conceptual and quantitative approach to exploring and defining potential open-access olfactory information. [PDF]

New Phytol, 2022
Orlando CG, Possell M, Price C, Banks PB, Mercorelli L, McArthur C.   +5 more
europepmc   +1 more source

Discovering Discovery: Non-Party Access to Pretrial Information in the Federal Courts 1938-2006 [PDF]

, 2007
In the modern era, the pretrial process is critical to the disposition of almost all litigation. The vast majority of cases never go to trial. Those which are contested at trial and upon appeal are often decided upon the results of the information gather
Moskowitz, Seymour
core   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Access to Information and Communication Technology, Digital Skills, and Perceived Well-Being among Older Adults in Hong Kong. [PDF]

Int J Environ Res Public Health, 2023
Fung KK, Hung SS, Lai DWL, Shum MHY, Fung HW, He L.   +5 more
europepmc   +1 more source

Access Control to Internet Information Sources [PDF]

, 2010
Import 29/09/2010V předložené práci je zpracován přehled možností řízení přístupu k internetovým informačním zdrojům. V první části práce je zpracován přehled možností přístupu k internetovým informačním zdrojům s ukázkou zavedených systému pro jejich ...
Šacl, Jan
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Access to Information, and Concerns, Myths and Truths about Food Safety during the COVID-19 Pandemic: An Overview of the Portuguese Population. [PDF]

Foods, 2023
Lemos M, Maia RL, Teixeira P.
europepmc   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source