Results 121 to 130 of about 10,763,224 (335)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Promoting Environmental Justice through Civil-Based Instruments in South Africa [PDF]

open access: yesLaw, Environment and Development Journal, 2017
Achieving environmental justice in South Africa is critically important, not only because of historical reasons rooted in the country’s apartheid past, but also to ensure that everyone in the country, especially marginalized and vulnerable sectors of ...
Michelle Toxopeüs and Louis J. Kotzé
doaj  

Promoting Improved Access to Consumer Health Information [PDF]

open access: yes, 2005
“Do you have any information on lupus?” “What are the side effects of Prozac?” “I want to find an herbal remedy for arthritis.” Questions such as these are asked each day across the country at public library reference desks.
Kaiser, Josephine
core  

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Access to information on gender-based violence prevention during COVID-19 lockdown in Uganda: a cross-sectional study. [PDF]

open access: yesEClinicalMedicine, 2023
Bukuluki P   +10 more
europepmc   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Mental Health and Access to Information in Times of COVID-19: The Role of Social Work. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Romea AC, Valero D, Elboj C, Melgar P.
europepmc   +1 more source

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