Results 141 to 150 of about 5,022,759 (359)

Lack of information and access to advanced treatment for Parkinson’s disease patients

open access: yesJournal of Multidisciplinary Healthcare, 2011
J Lökk1,21Department of Neurobiology, Caring Sciences and Society, The Karolinska Institute, 2Karolinska University Hospital Huddinge, Stockholm, SwedenBackground: Parkinson’s disease (PD) patients’ own knowledge and ...
Lökk J
doaj  

Beyond Release: Access Considerations for Generative AI Systems [PDF]

open access: yesarXiv
Generative AI release decisions determine whether system components are made available, but release does not address many other elements that change how users and stakeholders are able to engage with a system. Beyond release, access to system components informs potential risks and benefits.
arxiv  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Promoting Environmental Justice through Civil-Based Instruments in South Africa [PDF]

open access: yesLaw, Environment and Development Journal, 2017
Achieving environmental justice in South Africa is critically important, not only because of historical reasons rooted in the country’s apartheid past, but also to ensure that everyone in the country, especially marginalized and vulnerable sectors of ...
Michelle Toxopeüs and Louis J. Kotzé
doaj  

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, EarlyView.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

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