Results 101 to 110 of about 7,433,094 (307)

Open Access to Scientific Knowledge

open access: yesDESIDOC Journal of Library & Information Technology, 2008
The open access movement, well known in the domain of journal articles, came about because of several reasons. These include scholars’ and researchers‘ willingness to share knowledge, and advances in technology which enabled opening up free access to information.
openaire   +1 more source

Integrating Genomic Knowledge Sources through an Anatomy Ontology [PDF]

open access: yes, 2004
Modern genomic research has access to a plethora of knowledge sources. Often, it is imperative that researchers combine and integrate knowledge from multiple perspectives.
Gennari, John H   +2 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Bridging the digital divide: libraries driving access to knowledge [PDF]

open access: yes, 2010
How can libraries bridge the digital divide?; Access to information; Technology; Information ...
Tise, Ellen R.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Access to the internet and access to knowledge

open access: yes, 2006
Subbiah Arunachalam, Public access to the Internet, a chapter in Word Matters: Multicultural perspectives on information societies, C & F Editions, 2005. Self-archived February 21, 2006.
openaire   +1 more source

Revitalizing African Libraries: The Challenge of a Quiet Crisis [PDF]

open access: yes, 2000
Explores issues of literacy, information technology, and access to global knowledge as they relate to African public and university libraries.

core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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