Results 111 to 120 of about 94,242,737 (296)
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Journal of Management and Research, 2018 The importance of small and medium enterprises (SMEs) and their economic contribution is acknowledged globally. Although SMEs in developed economies have become fairly competitive, their counterparts in the emerging economies have struggled in the ...
Khansa Masood +2 more
doaj
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
, 2009 This is a two-page seminar report on a presentation of research findings of the African Copyright and Access to Knowledge Network (ACA2K) that follows the activities of a network of over 30 independent experts from law, economics, information sciences ...
core +1 more source
, 2006 Gilad Mishne, Information Access Challenges in the Blogspace, a paper to be presented at the International Workshop on Intelligent Information Access (Helsinki, July 6-8, 2006). (Thanks to ResourceShelf.)
openaire +1 more source
Protecting Health Workers from Exposure to Occupational Violence [PDF]
, 2015 K2P Briefing Notes quickly and effectively advise policymakers and stakeholders about a pressing public issue by bringing together global research evidence and local evidence.
Alameddine, Mohammad +4 more
core
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Informing Salt Iodization Policies in Lebanon to Ensure Optimal Iodine Nutrition [PDF]
, 2016 K2P Policy Briefs bring together global research evidence, local evidence and context-specific knowledge to inform deliberations about health policies and programmes.
Akik, Chaza +4 more
core +2 more sources
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source