Results 91 to 100 of about 7,433,094 (307)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Determinants of Reproductive Health Behavior among Adolescents: A Cross-Sectional Study

Jurnal Ilmiah Kesehatan Sandi Husada
Introduction: Adolescents are vulnerable to reproductive health problems due to limited knowledge, inadequate access to information, and a lack of family support.
Putu Noviana Sagitarini, Ni Komang Tri Agustini, Ida Ayu Ningrat Pangruating Diyu, Ni Made Candra Citra Sari   +3 more
doaj   +1 more source

Building evidence into youth health policy: a case study of the Access 3 knowledge translation forum. [PDF]

Health Res Policy Syst, 2022
Waller D, Robards F, Schneider CH, Sanci L, Steinbeck K, Gibson S, Usherwood T, Hawke C, Jan S, Kong M, Kang M.   +10 more
europepmc   +1 more source

Open access repository for the brazilian literature on agroecology. [PDF]

, 2010
The Brazilian technical and scientific literature on Agroecology is plentiful, is scattered and of difficult access and the hypothesis is that the knowledge of the area was produced but is composed by a knowledge to be organized.
Alencar, Maria de Cléofas Faggion
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Open educational resources - new directions for technology-enhanced distance learning in the third millennium [PDF]

, 2008
Open Educational Resources (OERs) are an innovation giving new opportunities for learning and distance education. OERs are typically provided as courses but also include smaller units of learning and their components of audio, text or image files made ...
Godwin, Steve, McAndrew, Patrick, Santos, Andreia   +2 more
core   +1 more source

Lewy Body Dementia Association\u27s Research Centers of Excellence Program: Inaugural Meeting Proceedings. [PDF]

, 2019
The first Lewy Body Dementia Association (LBDA) Research Centers of Excellence (RCOE) Investigator\u27s meeting was held on December 14, 2017, in New Orleans.
Amodeo, Katherine, Armstrong, Melissa, Barrett, Matt, Boeve, Brad, Christie, Tina, Domoto-Reilly, Kimiko, Duda, John, Galasko, Douglas, Galvin, James E., Goldman, Jennifer, Gomperts, Stephen, Graff-Radford, Neill, Graham, Todd, Holden, Samantha, Honig, Lawrence, Huddleston, Daniel, Irwin, David, Kaufer, Daniel, Koehler, Mike, Leverenz, James, Lippa, Carol, Litvan, Irene, Lunde, Angela, Manning, Carol, Marder, Karen, McKeith, Ian G., Moussa, Charbel, Onyike, Chiadi, Pagan, Fernando, Pantelyat, Alexander, Paulson, Henry, Pelak, Victoria, Peterson, Bethany, Poston, Kathleen, Quinn, Joseph, Richard, Irene, Richards, Ian, Rosenthal, Liana S., Sabbagh, Marwan, Scharre, Douglas, Sha, Sharon, Shill, Holly, Siderowf, Andrew, Taylor, Angela, Torres-Yaghi, Yasar   +44 more
core   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Evaluation of an Access-Risk-Knowledge (ARK) Platform for Governance of Risk and Change in Complex Socio-Technical Systems. [PDF]

Int J Environ Res Public Health, 2021
McDonald N, McKenna L, Vining R, Doyle B, Liang J, Ward ME, Ulfvengren P, Geary U, Guilfoyle J, Shuhaiber A, Hernandez J, Fogarty M, Healy U, Tallon C, Brennan R.   +14 more
europepmc   +1 more source

Access to Knowledge Treaty

, 2005
WIPO is considering an Access to Knowledge Treaty as part of its development agenda. (In case you've forgotten, this is not your father's WIPO. The development agenda has promising implications for OA.) If you have ideas for the treaty, then send them to the a2k (Access to Knowledge) email list or to Jamie Love.
openaire   +1 more source