Results 71 to 80 of about 2,718,889 (304)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Leveraging Vascular Access Team to increase safety and access to care

open access: yes, 2023
Using a pager platform to receive vascular access consults related to peripheral intravenous catheter (PIV)/central line care and maintenance needs has resulted in significant time and delays in treatment lost by bedside nursing and vascular access staff.
Linscott, Deb   +3 more
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ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

ACA2K methodology guide [PDF]

open access: yes, 2008
French version available in IDRC Digital Library: D2ASA : guide méthodologiquePortuguese version available in IDRC Digital Library: Guia de metodologia do ...

core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

MOOCs as "Semicommons" in the Knowledge Commons Framework

open access: yesThe African Journal of Information and Communication, 2016
The commons approach to knowledge governance is an increasingly popular and successful model for mediating and explaining the ways in which knowledge producers and users, institutions, and shared information resources, interact in social and cultural ...
Kyle Rother
doaj   +3 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Guia de metodologia do ACA2K [PDF]

open access: yes, 2008
Texto en portugúesVersión en inglés disponible en la Biblioteca Digital del IDRC: ACA2K methodology guideVersión en francés disponible en la Biblioteca Digital del IDRC: D2ASA : guide ...

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Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

ترشيد آلية تصميم وتنفيذ برنامج البطاقة التمويلية الذي أقر في مجلس النواب اللبناني

open access: yes, 2021
النسخة الإنجليزية: Informing the Design and Implementation of the Newly Approved Cash Transfer Program by the Parliament of Lebanon http://hdl.handle.net/10938/34825In response to the unprecedented economic and financial crisis, the Parliament of Lebanon
Abou Samra, Clara   +4 more
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