The infinitely many genes model with horizontal gene transfer
The genome of bacterial species is much more flexible than that of eukaryotes. Moreover, the distributed genome hypothesis for bacteria states that the total number of genes present in a bacterial population is greater than the genome of every single ...
Baumdicker, Franz, Pfaffelhuber, Peter
core +1 more source
The use of whole-genome phylogenetic analysis has revolutionized our understanding of the evolution and spread of many important bacterial pathogens due to the high resolution view it provides.
Alan McNally +20 more
doaj +1 more source
Destabilization of chromosome structure by histone H3 lysine 27 methylation.
Chromosome and genome stability are important for normal cell function as instability often correlates with disease and dysfunction of DNA repair mechanisms.
Mareike Möller +10 more
doaj +1 more source
Proficient replication of the yeast genome by a viral DNA polymerase [PDF]
DNA replication in eukaryotic cells requires minimally three B-family DNA polymerases: Pol α, Pol δ, and Pol ϵ. Pol δ replicates and matures Okazaki fragments on the lagging strand of the replication fork.
Burgers, Peter M +2 more
core +2 more sources
Genomic comparison of diverse Salmonella serovars isolated from swine. [PDF]
Food animals act as a reservoir for many foodborne pathogens. Salmonella enterica is one of the leading pathogens that cause food borne illness in a broad host range including animals and humans.
Barrett, John B +9 more
core +2 more sources
Dispensable genome and segmental duplications drive the genome plasticity in Fusarium solani
Fusarium solani is a species complex encompassing a large phylogenetic clade with diverse members occupying varied habitats. We recently reported a unique opportunistic F. solani associated with unusual dark galls in sugarbeet.
Abbeah Navasca +5 more
doaj +1 more source
The Plasmid Mobilome of the Model Plant-Symbiont Sinorhizobium meliloti: Coming up with New Questions and Answers [PDF]
Rhizobia are Gram-negative Alpha- andBetaproteobacteria living in the underground that have theability to associate with legumes for the establishment ofnitrogen-fixing symbioses.Sinorhizobium melilotiinparticular—the symbiont ofMedicago,Melilotus ...
Lagares, Antonio +2 more
core +2 more sources
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Pseudomonas aeruginosa genomic structure and diversity
The Pseudomonas aeruginosa genome (G + C content 65-67%, size 5.5 – 7 Mbp) is made up of a single circular chromosome and a variable number of plasmids. Sequencing of complete genomes or blocks of the accessory genome has revealed that the genome encodes
Jens eKlockgether +4 more
doaj +1 more source
Detailed evaluation of data analysis tools for subtyping of bacterial isolates based on whole genome sequencing : Neisseria meningitidis as a proof of concept [PDF]
Whole genome sequencing is increasingly recognized as the most informative approach for characterization of bacterial isolates. Success of the routine use of this technology in public health laboratories depends on the availability of well-characterized ...
Bertrand, Sophie +5 more
core +1 more source

