Results 61 to 70 of about 71,406 (306)
Advanced Science, EarlyView.ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
Heat\ua0stress : acclimatization
New employees are at the highest risk for heat illness. Acclimatization is crucial to working in hot conditions. Things you need to know: 1. Heat acclimatization is the improvement in heat tolerance that comes from gradually increasing the intensity or ...
core +1 more source
Serum ferritin during high altitude acclimatization and de-acclimatization.
, 2014 Data are presented as mean ± SD (ng ml−1) with the number of subjects indicated in parentheses. The POST measurement took place upon initial return to 5260 m following descent to 1525 m for 7 days (7W, 7M) or 21 days (2W, 4M) duration. Linear mixed model
Benjamin J. Ryan (541039) +7 more
core +1 more source
Advanced Science, EarlyView.Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang +10 more
wiley +1 more source
Structural Modifications of the Brain in Acclimatization to High-Altitude
, 2010 Adaptive changes in respiratory and cardiovascular responses at high altitude (HA) have been well clarified. However, the central mechanisms underlying HA acclimatization remain unclear.
Yan, Xiaodan +6 more
core +1 more source
Plant, Soil and Environment, 2002 Powdery mildew on barley (Hordeum vulgare L.) caused by the pathogen Blumeria graminis f.sp. hordei occurs worldwide and can result in severe yield loss.
J.H. Czembor, H.J. Czembor
doaj +1 more source
DArT-based evaluation of soybean germplasm from Polish Gene Bank
BMC Research Notes, 2021 Objective Soybean is an important plant used for food, feed and many industrial purposes. Interest in soybean breeding is growing in Central Europe, including Poland. A very large number of soybean accessions are stored in gene banks, but less than 1% of
Elzbieta Czembor +3 more
doaj +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Fusarium head blight resistance and mycotoxin profiles of four Triticum species genotypes
Phytopathologia Mediterranea, 2017 Fusarium head blight (FHB) resistance was evaluated for accessions of four Triticum species, including bread wheat (modern and old cultivars), spelt, emmer, and einkorn.
Tomasz GÓRAL, Piotr OCHODZKI
doaj +1 more source
Advanced Science, EarlyView.The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun +7 more
wiley +1 more source