Results 71 to 80 of about 36,028 (257)

Down syndrome: a review of ocular manifestations

Therapeutic Advances in Ophthalmology, 2022
Down syndrome is the most common genetically mediated intellectual disability. Although many physiologic and pathologic features of Down syndrome are discussed at length in the literature, the ocular manifestations of Down syndrome have seldom been ...
Abid Haseeb, Elisah Huynh, Reem H. ElSheikh, Ahmed S. ElHawary, Christina Scelfo, Danielle M. Ledoux, Daniel E. Maidana, Abdelrahman M. Elhusseiny   +7 more
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Accommodative convergence–accommodation ratio and fusional capacity in patients with constant and intermittent exotropia

Journal of Ophthalmology, 2021
Background: It has been reported that exotropia was seen in 16.9-23% of patients with strabismus. Exophoria and exotropia may be caused by congenital or acquired anomalies in orbital structure, ocular structure, or extraocular muscle attachment and/or ...
I. M. Boichuk, Alui Tarak
doaj   +1 more source

Using Eye Tracker To Evaluate Cockpit Design -- A Flight Simulation Study [PDF]

Aviation 2022, 2021
This paper investigates applications of eye tracking in transport aircraft design evaluations. Piloted simulations were conducted for a complete flight profile including take off, cruise and landing flight scenario using the transport aircraft flight simulator at CSIR National Aerospace Laboratories.
arxiv  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Axial movement of the dual-optic accommodating intraocular lens for the correction of the presbyopia: Optical performance and clinical outcomes

Journal of Optometry, 2015
Presbyopia occurs in the aging eye due to changes in the ciliary muscle, zonular fibers, crystalline lens, and an increased lens sclerosis. As a consequence, the capacity of accommodation decreases, which hampers to focus near objects.
Javier Tomás-Juan, Ane Murueta-Goyena Larrañaga   +1 more
doaj   +1 more source

Ocular Recognition Databases and Competitions: A Survey [PDF]

, 2019
The use of the iris and periocular region as biometric traits has been extensively investigated, mainly due to the singularity of the iris features and the use of the periocular region when the image resolution is not sufficient to extract iris information.
arxiv   +1 more source

Estimation of the mechanical properties of the eye through the study of its vibrational modes

, 2017
Measuring the eye's mechanical properties in vivo and with minimally invasive techniques can be the key for individualized solutions to a number of eye pathologies.
Adsuara, J. E., Aloy, M. A., Cerdá-Durán, P., Esteve-Taboada, J. J., Ferrer-Blasco, T., Montés-Micó, R., Obergaulinger, M.   +6 more
core   +3 more sources

The Cambridge Anti-myopia Study: variables associated with myopia progression [PDF]

, 2013
Purpose: To identify variables associated with myopia progression and to identify any interaction between accommodative function, myopia progression, age, and treatment effect in the Cambridge Anti-Myopia Study. Methods: Contact lenses were used
Allen, Peter M., Calver, Richard I., O'Leary, Daniel J., Price, Holly C., Radhakrishnan, Hema, Rae, Sheila M., Sailoganathan, Ananth, Theagarayan, Baskar P.   +7 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source