Results 121 to 130 of about 305,897 (326)

Evolution of the Shoreline Between the Ports of Valencia and Sagunto, Spain (1957–2024)

open access: yesJournal of Marine Science and Engineering
Coastal areas are increasingly affected by erosion due to climate change and human interventions, threatening the stability of many shorelines. Understanding coastal dynamics is therefore crucial for developing effective conservation and management ...
Joan Ortiz Vivas   +2 more
doaj   +1 more source

The Baryonic Assembly of Dark Matter Halos

open access: yes, 2011
We use a suite of cosmological hydrodynamic simulations to quantify the accretion rates of baryons into dark matter halos and the resulting baryon mass fractions, as a function of halo mass, redshift, and baryon type (including cold and hot gas). We find
Adelberger   +122 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Accretion in stellar clusters and the initial mass function [PDF]

open access: bronze, 2001
I. A. Bonnell   +3 more
openalex   +1 more source

MASS ACCRETION RATE OF ROTATING VISCOUS ACCRETION FLOW [PDF]

open access: yesThe Astrophysical Journal, 2009
15 pages, 3 figures, to appear in ...
openaire   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Luminous Hot Accretion Disks [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2001
We find a new two-temperature hot branch of equilibrium solutions for stationary accretion disks around black holes. In units of Eddington accretion rate defined as $10L_{\rm Edd}/c^2$, the accretion rates to which these solutions correspond are within the range $\dot{m}_1 \la \dot{m} \la 1$, here $\dot{m}_1$ is the critical rate of advecti$.
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy