Results 111 to 120 of about 278,789 (290)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

HR6819: a puffed-up stripped star system challenging stable mass transfer theory

Astronomy & Astrophysics
Context. HR6819 is the first system with a puffed-up low-mass stripped star + a classical Be star whose nature has been confirmed by optical interferometry.
Picco A., Marchant P., Sana H., Bodensteiner J., Shenar T., Frost A. J., Deshmukh K., Mombarg J. S. G., Pauli D., Willcox R., Kemp A.   +10 more
doaj   +1 more source

Observational limits on type 1 active galactic nucleus rate in COSMOS [PDF]

, 2009
We present black hole masses and accretion rates for 182 Type 1 active galactic nuclei (AGNs) in COSMOS. We estimate masses using the scaling relations for the broad H β, Mg ii, and C iv emission lines in the redshift ranges 0.16 < z < 0.88, 1 < z < 2 ...
Bongiorno, Angela, Brusa, Marcella, Cappelluti, Nico, Elvis, Martin, Gabor, Jared, Hao, Heng, Huchra, John P., Impey, Chris D., Kelly, Brandon C., Koekemoer, A., McCarthy, Patrick J., Merloni, Andrea, Nagao, Tohru, Salvato, Mara, Scoville, Nick Z., Trump, Jonathan R.   +15 more
core  

Stable accretion from a cold disc in highly magnetized neutron stars

, 2017
The aim of this paper is to investigate the transition of a strongly magnetized neutron star into the accretion regime with very low accretion rate. For this purpose we monitored the Be-transient X-ray pulsar GRO J1008-57 throughout a full orbital cycle.
Abolmasov, P. K., Doroshenko, V., Lutovinov, A. A., Mushtukov, A. A., Poutanen, J., Suleimanov, V. F., Tsygankov, S. S.   +6 more
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

XMM-Newton multi-year campaign on NGC 55 ULX-1

Astronomy & Astrophysics
Context. Winds are an important ingredient in the evolution of X-ray binary (XRB) systems, particularly those at high accretion rates such as ultra-luminous X-ray sources (ULXs), because they may regulate the accretion of matter onto the compact object ...
Pinto C., Caserta S., Barra F., Xu Y., Barret D., Kosec P., La Palombara N., Marino A., Pintore F., Riggio A., Roberts T. P., Salvaggio C., Sidoli L., Soria R., Walton D. J.   +14 more
doaj   +1 more source

General-Relativistic Simulations of Four States of Accretion onto Millisecond Pulsars

, 2017
Accreting neutron stars can power a wide range of astrophysical phenomena including short- and long-duration gamma-ray bursts, ultra-luminous X-ray sources, and X-ray binaries.
Parfrey, Kyle, Tchekhovskoy, Alexander
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Paradox of the Moving Boundary: Legal Heredity of River Accretion and Avulsion

Water Alternatives, 2011
International boundaries – the divisions between state jurisdictions – are characterised in law by their inherent rigidity. Yet recent research has revealed that well over one-third of the total length of international boundaries follow rivers or streams
John W. Donaldson
doaj  

Double-hump spectrum, pulse profile dip, and pulsed fraction spectra from the low-accretion regime in the X-ray pulsar MAXI J0655-013

Astronomy & Astrophysics
Context. Accreting X-ray pulsars (XRPs) undergo different physical regimes depending on different mass accretion rates, with related changes in the emitted X-ray spectral properties.
Malacaria C., Pike S. N., D’Aì A., Israel G. L., Ducci L., Rothschild R. E., Stella L., Amato R., Ambrosi E., Coley J. B., Fürst F., Imbrogno M., Kretschmar P., Maniadakis D. K., Papitto A., Pradhan P., Rouco Escorial A., Simongini A., Stierhof J., West B. F., Zalot N.   +20 more
doaj   +1 more source