Results 91 to 100 of about 26,473 (258)

Evolution of the Shoreline Between the Ports of Valencia and Sagunto, Spain (1957–2024)

Journal of Marine Science and Engineering
Coastal areas are increasingly affected by erosion due to climate change and human interventions, threatening the stability of many shorelines. Understanding coastal dynamics is therefore crucial for developing effective conservation and management ...
Joan Ortiz Vivas, Ana María Blázquez Morilla, Borja Martínez-Clavel Valles   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Cyclic light variations and accretion disk evolution in the Large Magellanic Cloud eclipsing binary OGLE-LMC-DPV-062

Astronomy & Astrophysics
Context. Many intermediate-mass close binaries exhibit photometric cycles longer than their orbital periods, likely linked to variations in their accretion disks.
Mennickent R. E., Djurašević G., Rosales J. A., Garcés J., Petrović J., Schleicher D. R. G., Soszyński I.   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

The elusive cyclotron line in 4U 1901+03: Hidden, yet present

Astronomy & Astrophysics
Context. Cyclotron resonant scattering features in accreting X-ray pulsars are often difficult to detect, especially when shallow or variable. Recent studies have shown that combining spectral and timing analyses enhances their detectability. Aims.
Ambrosi Elena, D’Aí Antonino, Cusumano Giancarlo, Ferrigno Carlo, Sokolova-Lapa Ekaterina, Maniadakis Dimitrios K., Tutone Antonio, Vasilopoulos Georgios, Kretschmar Peter, Malacaria Christian, Pintore Fabio   +10 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

A deep X-ray and UV look into the reflaring stage of the accreting millisecond pulsar SAX J1808.4−3658

Astronomy & Astrophysics
We present a detailed X-ray and UV high-time-resolution monitoring of the final reflaring phase of the 2022 outburst of the accreting millisecond pulsar SAX J1808.4−3658, based on simultaneous XMM-Newton and Hubble Space Telescope (HST) observations. The
Ballocco C., Papitto A., Miraval Zanon A., Illiano G., Di Salvo T., Ambrosino F., Burderi L., Campana S., Coti Zelati F., Di Marco A., Malacaria C., Pilia M., Poutanen J., Salmi T., Sanna A.   +14 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Optical Variability of Active Galactic Nuclei

Frontiers in Astronomy and Space Sciences, 2017
Szymon Kozłowski
doaj   +1 more source

Spiral formation caused by late infall onto protoplanetary disks

Astronomy & Astrophysics
The classical picture that planet formation occurs in protoplanetary disks that are isolated from their environment is undergoing a major shift toward a more connected picture.
Hühn L.-A., Kimmig C. N., Dullemond C. P.   +2 more
doaj   +1 more source