Results 101 to 110 of about 118,894 (281)
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Development and Evolution of the Rattlesnake Creek Terrane, Klamath Mountains, Northern California
The basement of the Rattlesnake Creek terrane (RCT) in the Klamath Mountains is a mélange of metamorphosed sedimentary and igneous blocks. Recent work shows that the overlying RCT cover sequence has a North American provenance but formed after accretion ...
Diana Urda +2 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Evolution of the Shoreline Between the Ports of Valencia and Sagunto, Spain (1957–2024)
Coastal areas are increasingly affected by erosion due to climate change and human interventions, threatening the stability of many shorelines. Understanding coastal dynamics is therefore crucial for developing effective conservation and management ...
Joan Ortiz Vivas +2 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Context. Many intermediate-mass close binaries exhibit photometric cycles longer than their orbital periods, likely linked to variations in their accretion disks.
Mennickent R. E. +6 more
doaj +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
The elusive cyclotron line in 4U 1901+03: Hidden, yet present
Context. Cyclotron resonant scattering features in accreting X-ray pulsars are often difficult to detect, especially when shallow or variable. Recent studies have shown that combining spectral and timing analyses enhances their detectability. Aims.
Ambrosi Elena +10 more
doaj +1 more source
Accretion disk radii changes in IP Peg during outburst
The focus of this study is the change in accretion disk size in Dwarf Novae (DN), IP Peg. DN systems are a type of cataclysmic variable that experience periodic outbursts.
Hamper, Randall T.
core
Accretion-induced Collapse from Helium Star + White Dwarf Binaries
<p>MESA other_wind_hook that limits the mass transfer to an accretor and can set the angular momentum of the mass loss, as in <a href="https://ui.adsabs.harvard.edu/?#abs/2017ApJ...843..151B">Accretion-induced Collapse from ...
Bildsten, Lars +9 more
core +1 more source

