Results 71 to 80 of about 26,473 (258)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

X-ray and radio observations of the AMXP MAXI J1957+032 covering the 2022–2025 outbursts

Astronomy & Astrophysics
We presented a comprehensive multi-epoch timing and multiwavelength analysis of the accreting millisecond X-ray pulsar MAXI J1957+032, covering two major outbursts in 2022 and 2025.
Li Zhaosheng, Kuiper Lucien, Pan Yuanyue, Xu Renxin, Ge Mingyu, Weng Shanshan, Peng Long, Yu Wenhui, Huang Yue, Zhang Liang, Song Liming, Molkov Sergey V., Lutovinov Alexander A., Zhang Shu, Zhang Shuang-Nan   +14 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Interaction between disk and extended corona in a general relativistic framework

Astronomy & Astrophysics
Context. The energy equilibrium between the corona and the underlying disk in a two-phase accretion flow sets a lower limit on the achievable photon index.
Datta Sudeb Ranjan, Bursa Michal, Dovciak Michal, Zhang Wenda   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

XMM-Newton multi-year campaign on NGC 55 ULX-1

Astronomy & Astrophysics
Context. Winds are an important ingredient in the evolution of X-ray binary (XRB) systems, particularly those at high accretion rates such as ultra-luminous X-ray sources (ULXs), because they may regulate the accretion of matter onto the compact object ...
Pinto C., Caserta S., Barra F., Xu Y., Barret D., Kosec P., La Palombara N., Marino A., Pintore F., Riggio A., Roberts T. P., Salvaggio C., Sidoli L., Soria R., Walton D. J.   +14 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Double-hump spectrum, pulse profile dip, and pulsed fraction spectra from the low-accretion regime in the X-ray pulsar MAXI J0655-013

Astronomy & Astrophysics
Context. Accreting X-ray pulsars (XRPs) undergo different physical regimes depending on different mass accretion rates, with related changes in the emitted X-ray spectral properties.
Malacaria C., Pike S. N., D’Aì A., Israel G. L., Ducci L., Rothschild R. E., Stella L., Amato R., Ambrosi E., Coley J. B., Fürst F., Imbrogno M., Kretschmar P., Maniadakis D. K., Papitto A., Pradhan P., Rouco Escorial A., Simongini A., Stierhof J., West B. F., Zalot N.   +20 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Paradox of the Moving Boundary: Legal Heredity of River Accretion and Avulsion

Water Alternatives, 2011
International boundaries – the divisions between state jurisdictions – are characterised in law by their inherent rigidity. Yet recent research has revealed that well over one-third of the total length of international boundaries follow rivers or streams
John W. Donaldson
doaj