Results 141 to 150 of about 305,897 (326)

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Paradox of the Moving Boundary: Legal Heredity of River Accretion and Avulsion

Water Alternatives, 2011
International boundaries – the divisions between state jurisdictions – are characterised in law by their inherent rigidity. Yet recent research has revealed that well over one-third of the total length of international boundaries follow rivers or streams
John W. Donaldson
doaj  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Phantom energy accretion and primordial black holes evolution in Brans–Dicke theory [PDF]

, 2011
Bibekananda Nayak, L. P. Singh
openalex   +1 more source

Accretion of Planetary Material onto Host Stars

, 2017
Accretion of planetary material onto host stars may occur throughout a star's life. Especially prone to accretion, extrasolar planets in short-period orbits, while relatively rare, constitute a significant fraction of the known population, and these ...
A Koenigl, A McQuillan, A Skumanich, A. Bonsor, A. P. Showman, Alexander J. Mustill, Avi M. Mandell, B Paczyński, B Zuckerman, B. D. Metzger, B. Levrard, Bill Paxton, BJR Davidsson, BMS Hansen, Brian Jackson, Brian Jackson, Brian Jackson, Brian Jackson, CC Counselman III, CD Murray, Christa Van Laerhoven, Claudia Aguilera-Gómez, D Lai, D. E. Trilling, D. Huber, D. J. A. Brown, DA Fischer, Daniel C. Fabrycky, DC Richardson, Dimitri Veras, DNC Lin, DNC Lin, Elisabeth R. Adams, Eric B. Ford, Eunkyu Han, Eva Villaver, Eva Villaver, FA Rasio, Francesca Valsecchi, Francesca Valsecchi, G Wallerstein, Gordon I. Ogilvie, H Ritter, I Ramírez, IJ Sackmann, J Irwin, J Meléndez, J. Farihi, J. H. Steffen, J. Lillo-Box, J. Nordhaus, J. Setiawan, James Guillochon, JB Alexander, JE Chambers, JK Carlberg, John H. Debes, Joleen K. Carlberg, Joshua N. Winn, JR Stauffer, Julian C. van Eyken, K Batygin, Kaloyan Penev, Kevin C. Schlaufman, L Siess, L Siess, Lauren M. Weiss, M Deal, M Jura, M. Kunitomo, M. Livio, M. Nagasawa, Marcelo Tucci Maia, NA Drake, P Chayer, P Goldreich, P Goldreich, Pin‐Gao Gu, PP Eggleton, RA Mardling, Roberto Sanchis-Ojeda, Roberto Sanchis-Ojeda, S Barnes, S Teitler, Saul Rappaport, SD Kawaler, Shang-Fei Liu, Shi Jia, Simon Albrecht, Smadar Naoz, Soko Matsumura, Sourav Chatterjee, Sylvie Théado, Sylvio Ferraz-Mello, William D. Cochran, Z Kopal   +95 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

HIGH ENERGY NEUTRINOS PRODUCED IN THE ACCRETION DISKS BY NEUTRONS FROM NUCLEI DISINTEGRATED IN THE AGN JETS [PDF]

, 2016
W. Bednarek
openalex   +1 more source

Particle acceleration by magnetic Rayleigh-Taylor instability: Mechanism for flares in black hole accretion flows [PDF]

, 2023
Vladimir Zhdankin, Bart Ripperda, Alexander Philippov   +2 more
openalex   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source