Results 41 to 50 of about 26,045 (258)
Accretion disc particle accretion in major merger simulations [PDF]
A recent approach to simulating localized feedback from active galactic nuclei by Power et al. (2011) uses an accretion disc particle to represent both the black hole and its accretion disc. We have extrapolated and adapted this approach to simulations of Milky Way-sized galaxy mergers containing black holes and explored the impact of the various ...
Wurster, James Howard +1 more
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Karimunjawa National Park area has various coastal resources and ecosystems, such as mangrove forests, seagrass, and coral reefs, which provide a habitat for several vital organisms.
Suryanti Suryanti +3 more
doaj +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
49p. To appear in XXI Canary Islands Winter School of Astrophysics, ed. T. Shahbaz, CUP (significantly improved, expanded and updated version of an earlier text)
openaire +6 more sources
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Granitoids of the Ufaley Block: Geodynamic environments, age, sources, problems
There are complex of data about composition, age, isotopic parameters for granites from the Ufaley block, which is situated in the accretion zone on the boundary between the Urals and the East European platform.
G. Yu. Shardakova
doaj

