Results 41 to 50 of about 118,894 (281)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Accreted or Not Accreted? The Fraction of Accreted Mass in Galaxies from the Magneticum Simulations and Observations

open access: yesThe Astrophysical Journal, 2022
Abstract In the two-phase scenario of galaxy formation, a galaxy’s stellar mass growth is first dominated by in-situ star formation, and subsequently by accretion. We analyze the radial distribution of the accreted stellar mass in ∼500 galaxies from the (48 Mpc/h)3 box volume of the hydrodynamical cosmological simulation Magneticum, in a
Rhea-Silvia Remus, Duncan A. Forbes
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Modeling accretion columns in accretion-powered pulsars

open access: yesAstronomy & Astrophysics
Context. Accretion-powered X-ray pulsars show complex spectral and timing behavior that reflects the extreme conditions near the neutron star. Modeling these observables remains challenging, particularly at high mass-accretion rates, Ṁ ≳ 10 17
S. Falkner   +19 more
openaire   +1 more source

Massive star formation by accretion [PDF]

open access: yesAstronomy & Astrophysics, 2015
Massive stars likely form by accretion and the evolutionary track of an accreting forming star corresponds to what is called the birthline in the HR diagram. The shape of this birthline is quite sensitive to the evolution of the entropy in the accreting star.
Haemmerlé Lionel   +4 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Geospatial technology based shoreline change analysis (1992–2022) and predictive forecast modeling for 2032 and 2042, utilizing DSAS, along the eastern coast of India

open access: yesKuwait Journal of Science
This study presents a comprehensive analysis of shoreline dynamics in the Thanjavur district, focusing on erosion and accretion trends from 1992 to 2022. The coastal region was partitioned based on Taluk boundaries to discern distinct patterns in erosion
Harikrishna S.   +2 more
doaj   +1 more source

Super-Eddington Black Hole Accretion:

open access: yes, 2005
Is there an upper limit to the accretion rate dot M, preventing astrophysical black holes to swallow all the matter infalling into them? Many astrophysicists are convinced that the answer to this fundamental question should be: yes, the limit exist and ...
Abramowicz, Marek A,, M.A. Abramowicz
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Tectonic-geodynamical zoning of the Ural-Timan-Paleoasian segment of Eurasia

open access: yesЛитосфера, 2015
Methodology of geological zoning of orogenic belts, adequate to mobilistic paradigma, should be in a natural way correspond to geodynamics conception, taking into consideration the positions of lithospheric plate tectonics.
V. M. Necheukhin, E. N. Volchek
doaj  

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